...) and the NO (nitric oxide) donor sin-1 (3-morpholino-sydnonimine) in human by-pass grafts. In contrast with previous studies, the same vessel was used to demonstrate a direct link between cGMP production and functional relaxation. Remnants of the IMA (internal mammary artery) and SV (saphenous vein) were obtained...

... for each concentration was calculated as the percentage activity [(contraction to big ET-1/contraction to ET-1)×100] normalized to KCl (100mM). In control experiments, at low concentrations FEA was lower in internal mammary arteries than in saphenous veins ( P <0.05). While FEA was suppressed...

... antagonists in blocking the B-HT 933-induced contractile responses of the dog saphenous vein and preventing adrenaline-induced aggregation of human platelets. 5. Together with previously published data derived from tritium overflow studies on rabbit pulmonary arteries and displacement of [ 3 H]-rauwolscine...

... (37°-24°C) has the opposite effect. 2. The effects of warming and cooling on α 1 -adrenergic responses are buffered by a large receptor reserve, allowing for the predominance of alterations in α 2 -adrenergic responsiveness. α-adrenoceptors receptor reserve saphenous vein temperature © 1985...