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Keywords: senotherapeutic
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Articles
Alveolar epithelial cells of lung fibrosis patients are susceptible to severe virus-induced injury
Available to PurchaseJane Read, Andrew T. Reid, Claire Thomson, Marshall Plit, Ross Mejia, Darryl A. Knight, Muriel Lize, Karim El Kasmi, Christopher L. Grainge, Heiko Stahl, Michael Schuliga
Journal:
Clinical Science
Clin Sci (Lond) (2024) 138 (8): 537–554.
Published: 23 April 2024
... augmented virus-induced injuries in AECs (but not viral load), whereas selected senotherapeutics (rapamycin and mitoTEMPO) were protective. The present study provides evidence that senescence increases the susceptibility of AECs from PF patients to severe virus-induced injury and suggests targeting...
Includes: Supplementary data
