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Keywords: short-chain fatty acids
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Articles
In Collection
The biology of ageing: Geroscience and the exposome
Malindi Welathanthree, Damien J. Keating, Vaughan G. Macefield, Daniela Carnevale, Francine Z. Marques, Rikeish R. Muralitharan
Journal:
Clinical Science
Clin Sci (Lond) (2025) 139 (09): 431–447.
Published: 08 May 2025
... to the large intestine, and the pelvic ganglia innervate the rectum [ 65 ]. enteroendocrine cells hypertension microbiome short-chain fatty acids sympathetic nervous system vagus nerve The absence of gut microbiota is linked to increased gut-extrinsic sympathetic activity, as indicated...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (2): 289–302.
Published: 30 January 2020
...Yanling Chang; Yunyan Chen; Qiong Zhou; Chuan Wang; Lei Chen; Wen Di; Yu Zhang Preeclampsia (PE) is regarded as a pregnancy-associated hypertension disorder that is related to excessive inflammatory responses. Although the gut microbiota (GM) and short-chain fatty acids (SCFAs) have been related...
Includes: Supplementary data
Articles
Quantitative reduction in short-chain fatty acids, especially butyrate, contributes to the progression of chronic kidney disease
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (17): 1857–1870.
Published: 10 September 2019
... fibrosis, and persistent intestinal flora disturbance are common in CKD. Short-chain fatty acids (SCFAs), produced by the intestinal microbiota, have been previously reported to ameliorate kidney injury; however, the specific concentrations and types that are required to improve renal function remain...
Includes: Supplementary data
Articles
Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men
Available to PurchaseChristina M. van der Beek, Emanuel E. Canfora, Kaatje Lenaerts, Freddy J. Troost, Steven W.M. Olde Damink, Jens J. Holst, Ad A.M. Masclee, Cornelis H.C. Dejong, Ellen E. Blaak
Journal:
Clinical Science
Clin Sci (Lond) (2016) 130 (22): 2073–2082.
Published: 11 October 2016
...Christina M. van der Beek; Emanuel E. Canfora; Kaatje Lenaerts; Freddy J. Troost; Steven W.M. Olde Damink; Jens J. Holst; Ad A.M. Masclee; Cornelis H.C. Dejong; Ellen E. Blaak Gut microbial-derived short-chain fatty acids (SCFA) are believed to affect host metabolism and cardiometabolic risk...
Includes: Supplementary data
Articles
Interleukin-8 stimulates the migration of human colonic epithelial cells in vitro
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1999) 97 (3): 385–390.
Published: 24 August 1999
.... The short-chain fatty acids, acetate, propionate, butyrate and valerate, the activator of protein kinase C (phorbol-12-myristate-13-acetate) and tumour necrosis factor-α (TNF-α) all stimulated the secretion of IL-8. However, only the motogenic effect of TNF-α was dependent upon IL-8. In conclusion, IL-8...
Articles
The contribution of the large intestine to blood acetate in man
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1991) 80 (2): 177–182.
Published: 01 February 1991
... probably becomes more important when fermentation of carbohydrate is occurring. 15 8 1990 14 9 1990 © 1991 The Biochemical Society and the Medical Research Society 1991 acetate colon dietary fibre fermentation short-chain fatty acids ClinicalScience (1991) 80,177-182 177...