.... Three separate colon cancer cell lines (LS174T, T84 and MCA-38), when butyrate treated, demonstrated striking amplification of specific individual gangliosides. However, the total lipid-bound sialic acid content of gangliosides of butyrate-treated LS174T cells diminished. In contrast to earlier reports...

...S. Haq; P. Tutt; M. Haq; M. Crook 1. We have shown that serum total sialic acid is elevated in hypertriglyceridaemic patients showing the Frederickson's type IIB phenotype in comparison with normal subjects (2.30 ±0.34 versus 1.92 ± 0.32 mmol/l, P <0.02). Lipid-associated sialic acid was also...

...M. Crook; P. Tutt 1. Serum total sialic acid concentration, recently shown to be a cardiovascular risk factor, and also serum lipid-associated sialic acid concentration were measured in 15 patients with hypertriglyceridaemia (fasting serum triacylglycerol concentration > 2.3 mmol/l) showing...

...Mark E. Rogers; Dean T. Williams; Ratnam Niththyananthan; Michael W. Rampling; Kirsten E. Heslop; Desmond G. Johnston 1. Sialic acid moieties of erythrocyte membrane glycoproteins are the principal determinants of the negative charge on the cell surface. The resultant electrostatic repulsion...

... in neutrophils could not account for the differences observed. 28 5 1987 19 6 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 bacterial glycosidases Crohn's disease glycoconjugate glycoprotein mucin mucus sialic acid sialidases ulcerative colitis...

...Charles W. Hutton; Anthony P. Corfield; John R. Clamp; Paul A. Dieppe 1. Transient mild dermal inflammation was produced in rats by the subcutaneous injection of either carageenan or monosodium urate crystals. The activities of enzymes of the sialic acid metabolic pathway were measured in liver...

...Liisa Laitinen; Aaro Miettinen; Ilkka Tikkanen; Tom TÖrnroth; Stig Nordling 1. Glomerular sialic acid was chemically measured in rats with experimental proteinuria induced by N,N '-diacetylbenzidine (DAB) or with autoimmune Heymann nephritis. 2. In DAB nephrosis and in Heymann nephritis...

... material were examined for sialic acid by the thiobarbituric acid method. 3. Sialic acid was found in every stone in either the soluble and/or insoluble material. 4. The identity of sialic acid was confirmed by the absorption spectrum of the colour produced and by its release from the protein...

... patterns. 7 8 1979 26 11 1979 © 1980 The Biochemical Society and the Medical Research Society 1980 heart ferritin human serum ferritin isoelectric focusing microheterogeneity neuraminidase sialic acid Clinical Science (1980) 58.259-262 SHORT COMMUNICATION Sialic acid...

...A. De Bats; A. H. Gordon; E. L. Rhodes 1. The glomerular sialic acid content of kidneys from diabetic subjects, aged subjects and healthy young individuals was determined. 2. Similar mean sialic acid contents were found in the glomeruli of elderly diabetic subjects, and in age- and sex-matched non...