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1-15 of 15
Keywords: signal transduction
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (24): 2481–2498.
Published: 23 December 2019
... The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Hes Hey Notch receptors pulmonary arteries signal transduction vascular smooth muscle cells...
Articles
Takashi Obama, Toshiyuki Tsuji, Tomonori Kobayashi, Yamato Fukuda, Takehiko Takayanagi, Yoshinori Taro, Tatsuo Kawai, Steven J. Forrester, Katherine J. Elliott, Eric Choi, Alan Daugherty, Victor Rizzo, Satoru Eguchi
Journal:
Clinical Science
Clin Sci (Lond) (2015) 128 (9): 559–565.
Published: 11 February 2015
... of EGFR-linked signal transduction in mouse and human AAA ( A ) C57BL/6 mice were treated with Ang II plus BAPN with or without erlotinib as in Figure 1 . Representative staining of AA with Masson's Trichrome (MT) and the indicated antibodies were presented ( n =4 in each group, 200X). ( B ) Human aorta...
Includes: Supplementary data
Articles
Tatsuya Usui, Tomoki Sakatsume, Ryo Nijima, Kosuke Otani, Kyosuke Kazama, Tomoka Morita, Satoshi Kameshima, Muneyoshi Okada, Hideyuki Yamawaki
Journal:
Clinical Science
Clin Sci (Lond) (2014) 127 (8): 539–548.
Published: 02 July 2014
... proliferation and migration. Our novel data suggest DAPK3 as a pharmaceutical target for the prevention of hypertensive cardiovascular diseases. death-associated protein kinase 3 (DAPK3) growth factor hyperplasia hypertension signal transduction • DAPK3 is a serine/threonine kinase...
Articles
Lucas T. Parreiras-e-Silva, Rosana I. Reis, Geisa A. Santos, Marcelo Pires-Oliveira, João B. Pesquero, Marcelo D. Gomes, Rosely O. Godinho, Claudio M. Costa-Neto
Journal:
Clinical Science
Clin Sci (Lond) (2014) 127 (3): 185–194.
Published: 03 April 2014
... metabolism signal transduction ubiquitin–proteasome system In the present study, we made use of various approaches and tools, including in vitro assays with C2C12 cell myotubes, animal treatment with selective antagonists and the use of knockout mice, to address the contribution of the kinin B 1...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2012) 122 (8): 361–368.
Published: 14 December 2011
... [ 21 ]. Therefore ligand-independent activation of Axl is more typical during pathophysiological conditions with increases in oxidative stress and excess receptor expression. Axl autoimmunity cancer receptor tyrosine kinase signal transduction vascular disease Axl, an RTK (receptor...
Articles
Jing Li, Wanli Xuan, Ran Yan, Michael B. Tropak, Emilie Jean-St-Michel, Wenbin Liang, Rachel Gladstone, Peter H. Backx, Rajesh K. Kharbanda, Andrew N. Redington
Journal:
Clinical Science
Clin Sci (Lond) (2011) 120 (10): 451–462.
Published: 28 January 2011
... andrew.redington@sickkids.ca ). 17 9 2010 17 11 2010 8 12 2010 8 12 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 β-catenin limb ischaemia myocardial infarction signal transduction remote ischaemic preconditioning The phenomenon of local IPC...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2010) 118 (8): 519–526.
Published: 26 January 2010
... with ALI/ARDS [ 10 , 11 ]. Furthermore, anti-IL-8 autoantibody/IL-8 immune complexes are found in association with FcγRIIa (Fcγ receptor IIa) in pulmonary tissues from these patients [ 14 ]. acute lung injury FcγRIIa IgG receptor lung signal transduction ALI and the ARDS were first...
Articles
Maurício M. Lopes, Gustavo C. A. Ribeiro, Thais F. Tornatore, Carolina F. M. Z. Clemente, Vicente P. A. Teixeira, Kleber G. Franchini
Journal:
Clinical Science
Clin Sci (Lond) (2007) 113 (4): 195–204.
Published: 13 July 2007
... ). 19 1 2007 16 4 2007 11 5 2007 11 5 2007 focal adhesion kinase (FAK) heart failure hypertrophy myocardial fibrosis signal transduction volume overload Cardiac diseases often result in adverse remodelling of the left ventricle and progression to heart failure...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 109 (3): 227–241.
Published: 24 August 2005
... Society 2005 angiogenesis inflammation signal transduction tumour vascular endothelial growth factor (VEGF) vascular permeability Angiogenesis and vasculogenesis are regulated predominantly by several different growth factors and their associated RTKs (receptor tyrosine kinases...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 108 (3): 185–194.
Published: 18 February 2005
... amino acids apoptosis diabetes gene expression metabolism mitochondria signal transduction In vivo , the β-cell is constantly monitoring nutrient availability and metabolic status and can generate appropriate secondary stimulus-coupling signals in response to the most minor changes...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2004) 106 (1): 19–25.
Published: 01 January 2004
... Nick Anim-Nyame (e-mail n.anim@ic.ac.uk ). 29 1 2003 19 6 2003 30 7 2003 30 7 2003 © 2004 The Biochemical Society 2004 blood flow conducted dilatation pre-eclampsia signal transduction Clinical Science (2004) 106, 19 25 (Printed in Great Britain) 19 Impaired...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2003) 104 (4): 421–428.
Published: 20 March 2003
... 2003 2003 angiopoietin-2 cell culture cyclical stretch gene expression signal transduction Tie receptor 421Clinical Science (2003) 104, 421 428 (Printed in Great Britain) Cyclical mechanical stretch enhances angiopoietin-2 and Tie2 receptor expression in cultured human umbilical vein...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1997) 92 (5): 445–451.
Published: 01 May 1997
... characterized by inappropriate activation of growth factor signalling pathways. © 1997 The Biochemical Society and the Medical Research Society 1997 cell proliferation protein kinase signal transduction Clinical Science (1997) 92,445-45 I (Printed in Great Britain) 445 Glaxo/MRS Young Investigator...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (5): 527–537.
Published: 01 November 1996
... states that G-proteins undergo as they are activated and deactivated and has provided great insight into the kinetic models of G-protein-mediated signal transduction. 3. The regulation of adenylate cyclase has proven to be intriguing and complex. G sα activates all forms of mammalian adenylate cyclase...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1995) 89 (3): 227–232.
Published: 01 September 1995
...Samuel S. Lee; Jung-Min Pak; Shaun M. Medlicott; Arieh Bomzon 1. There is currently considerable interest in the role of locally produced vasodilators such as nitric oxide and adenosine in the pathogenesis of the peripheral vasodilatation of cirrhosis. However, the signal transduction pathways...