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Keywords: signal transduction
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Clin Sci (Lond) (2019) 133 (24): 2481–2498.
Published: 23 December 2019
... The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Hes Hey Notch receptors pulmonary arteries signal transduction vascular smooth muscle cells...
Clin Sci (Lond) (2015) 128 (9): 559–565.
Published: 11 February 2015
... of EGFR-linked signal transduction in mouse and human AAA ( A ) C57BL/6 mice were treated with Ang II plus BAPN with or without erlotinib as in Figure 1 . Representative staining of AA with Masson's Trichrome (MT) and the indicated antibodies were presented ( n =4 in each group, 200X). ( B ) Human aorta...
Includes: Supplementary data
Clin Sci (Lond) (2012) 122 (8): 361–368.
Published: 14 December 2011
... [ 21 ]. Therefore ligand-independent activation of Axl is more typical during pathophysiological conditions with increases in oxidative stress and excess receptor expression. Axl autoimmunity cancer receptor tyrosine kinase signal transduction vascular disease Axl, an RTK (receptor...
Clin Sci (Lond) (2005) 109 (3): 227–241.
Published: 24 August 2005
... Society 2005 angiogenesis inflammation signal transduction tumour vascular endothelial growth factor (VEGF) vascular permeability Angiogenesis and vasculogenesis are regulated predominantly by several different growth factors and their associated RTKs (receptor tyrosine kinases...
Clin Sci (Lond) (2005) 108 (3): 185–194.
Published: 18 February 2005
... amino acids apoptosis diabetes gene expression metabolism mitochondria signal transduction In vivo , the β-cell is constantly monitoring nutrient availability and metabolic status and can generate appropriate secondary stimulus-coupling signals in response to the most minor changes...
Clin Sci (Lond) (2003) 104 (4): 421–428.
Published: 20 March 2003
... 2003 2003 angiopoietin-2 cell culture cyclical stretch gene expression signal transduction Tie receptor 421Clinical Science (2003) 104, 421 428 (Printed in Great Britain) Cyclical mechanical stretch enhances angiopoietin-2 and Tie2 receptor expression in cultured human umbilical vein...
Clin Sci (Lond) (1997) 92 (5): 445–451.
Published: 01 May 1997
... characterized by inappropriate activation of growth factor signalling pathways. © 1997 The Biochemical Society and the Medical Research Society 1997 cell proliferation protein kinase signal transduction Clinical Science (1997) 92,445-45 I (Printed in Great Britain) 445 Glaxo/MRS Young Investigator...
Clin Sci (Lond) (1996) 91 (5): 527–537.
Published: 01 November 1996
... states that G-proteins undergo as they are activated and deactivated and has provided great insight into the kinetic models of G-protein-mediated signal transduction. 3. The regulation of adenylate cyclase has proven to be intriguing and complex. G sα activates all forms of mammalian adenylate cyclase...
Clin Sci (Lond) (1995) 89 (3): 227–232.
Published: 01 September 1995
...Samuel S. Lee; Jung-Min Pak; Shaun M. Medlicott; Arieh Bomzon 1. There is currently considerable interest in the role of locally produced vasodilators such as nitric oxide and adenosine in the pathogenesis of the peripheral vasodilatation of cirrhosis. However, the signal transduction pathways...