... 26 9 2016 4 10 2016 4 10 2016 © 2016 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society 2016 cardiac hypertrophy dual specific phosphatase 12 c-Jun N-terminal kinase (JNK) signalling pathway SP600125 • DUSP12 is a member...

... cardioprotective action by interruption of Akt- but not MAPK (mitogen-dependent protein kinase)-dependent signalling pathways. Additionally, inactivation of Akt by LY294002 offset the exacerbated hypertrophic response induced by AB in TRIM32-deficient mice. In conclusion, the present study indicates that TRIM32...

... the vascular endothelium barrier and subsequent interaction with lung epithelium [ 5 ]. adhesion molecule lung inflammation signalling pathway thrombin transcription factor The human ICAM-1 (pIC-339/0)/firefly luciferase was kindly provided by Dr P. T. van der Saag (Hubrecht Laboratory...

... for the functional regulation of GPCRs, including the transactivation of other signal transduction receptors and the activation of G-protein-independent pathways. The existence of such alternative mechanisms for signal transduction and the discovery of agonists that can preferentially trigger one signalling pathway...

..., SRF and the ERK pathway and these findings suggest that hypoxia induces hypertrophy via MURC expression. cardiac myocyte hypoxia muscle-restricted coiled-coil protein (MURC) signalling pathway transforming growth factor-β (TGF-β) • The expression of MURC, a hypertrophy-regulated...

... 6 2004 1 7 2004 1 7 2004 The Biochemical Society 2004 apoptosis atherogenesis growth factor inflammation oxidative stress plaque rupture signalling pathway The arterial wall is composed of an innermost layer of endothelial cells resting on a thin basal lamina...