... The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 hypertension diet-induced obesity potassium channels small arteries vascular tone All experiments and care of animals were approved by the Animal Experiments Inspectorate of the Danish Ministry...

...Rudolf SCHUBERT; Michael J. MULVANY The myogenic response of small arteries and arterioles has been shown to contribute significantly to autoregulation in different vascular beds. It is characterized by a constriction of the vessel after an increase of transmural pressure and a dilation...

...% compared with 10 ± 5% ( P < 0.01) for thoracic segments from cholesterol-fed animals. Cerebral, femoral and mesenteric small arteries exposed to acetylcholine (10 −9 -10 −4 mol/l) relaxed to the same degree as arteries from control rabbits. The responses to sodium nitroprusside and bradykinin...