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Keywords: smooth muscle
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Articles
Clin Sci (Lond) (2010) 119 (1): 19–36.
Published: 07 April 2010
...Scott Earley; Joseph E. Brayden TRP (transient receptor potential) channels play important roles in the regulation of normal and pathological cellular function. In the vasculature, TRP channels are present both in ECs (endothelial cells) and vascular SMCs (smooth muscle cells) and contribute to...
Articles
Clin Sci (Lond) (2010) 118 (2): 115–120.
Published: 15 January 2010
.... Correspondence: Professor Brian J. Lipworth (email brianlipworth@gmail.com). 24 8 2009 24 7 2009 18 8 2009 The Biochemical Society, London 2010 adrenoceptor airway hyper-responsiveness asthma β-blocker bronchoconstriction heart failure smooth muscle Regulation of human...
Articles
Clin Sci (Lond) (2006) 110 (2): 153–165.
Published: 17 January 2006
...Liming Jin; Arthur L. Burnett Penile erection is a complicated event involving the regulation of corpus cavernosal smooth muscle tone. Recently, the small monomeric G-protein RhoA and its downstream effector Rho-kinase have been proposed to be important players for mediating vasoconstriction in the...
Articles
Clin Sci (Lond) (2005) 109 (3): 335–342.
Published: 24 August 2005
... Biochemical Society 2005 cerebral artery coronary artery 5-HT (5-hydroxytryptamine) receptor plasma concentration in vitro pharmacology smooth muscle triptan The drugs used currently that act as acute abortive anti-migraine therapies are defined as agonists at 5-HT 1B/1D receptors...
Articles
Clin Sci (Lond) (2004) 106 (5): 541–546.
Published: 01 May 2004
...Chia-Hung YEN; Ying-Tung LAU 17β-Oestradiol (E 2 ; oestrogen) is known to increase endothelium-dependent vasodilatation and NO (nitric oxide) production. It is also known to decrease the response of VSMCs (vascular smooth muscle cells) to vasoconstrictors in vitro . E 2 induces a decrease in age...
Articles
Clin Sci (Lond) (2002) 103 (4): 347–353.
Published: 27 August 2002
... paclitaxel, were implanted. The absorption and elution characteristics of paclitaxel were established. Artery tissue remained viable at 72h when cultured closed, despite stent implantation. Specimens developed smooth muscle cell proliferation. The stents absorbed up to 127±29 μ g of paclitaxel, with a...
Articles
Clin Sci (Lond) (1999) 96 (2): 155–163.
Published: 01 February 1999
... 1999 nitric oxide smooth muscle subcutaneous small arteries vascular structure 155Clinical Science (1999) 96, 155 163 (Printed in Great Britain) Altered small artery morphology and reactivity in critical limb ischaemia C. HILLIER, R. D. SAYERS*, P. A. C. WATT , R. NAYLOR , P. R. F. BELL and...
Articles
Clin Sci (Lond) (1995) 89 (1): 45–52.
Published: 01 July 1995
... levels of α-smooth-muscle actin or proliferating cell nuclear antigen correlated with myosin heavy-chain levels in the glomeruli of rats with puromycin aminonucleoside nephrosis. None of the cellular components in the glomeruli was positive for either α-smooth-muscle actin or proliferating cell nuclear...
Articles
Clin Sci (Lond) (1987) 73 (3): 299–303.
Published: 01 September 1987
... 1987 autonomic regulation bronchial hyper-responsiveness heart-lung transplantation methacholine smooth muscle Clinical Science (1987) 73, 299-303 Bronchial hyper-responsiveness after human cardiopulmonary transplantation ALLAN R. GLANVILLE, eONOR M. BURKE, JAMES THEODORE, JOHN C. BALDWIN...
Articles
Clin Sci (Lond) (1986) 70 (S14): 7s–13s.
Published: 01 December 1986
...A. F. Brading; J. L. Mostwin; G. N. A. Sibley; M. J. Speakman © 1986 The Biochemical Society and the Medical Research Society 1986 bladder intracellular potentials smooth muscle urethra Clinical Science (1986) 70 (Suppl. 14), 7s-13s 7s The role of smooth muscle and its possible...
Articles
Clin Sci (Lond) (1986) 70 (6): 571–575.
Published: 01 June 1986
... smooth muscle responsiveness to stimulation. 10 1 1986 17 1 1986 © 1986 The Biochemical Society and the Medical Research Society 1986 asthma airway epithelial cells bronchial hyper-reactivity cyclo-oxygenase inhibition smooth muscle Clinical Science( 1986) 70, 571-575 571...
Articles
Clin Sci (Lond) (1985) 68 (s10): 47s–50s.
Published: 01 January 1985
...P. Leijten; C. Cauvin; N. Lodge; K. Saida; C. Van Breemen 1. We propose the following model of Ca 2+ mobilization by noradrenaline in vascular smooth muscle. Upon receptor occupation Ca 2+ from a labile small intracellular store on the inner plasmalemma is released. This Ca 2+ does not function as...
Articles
Clin Sci (Lond) (1985) 68 (s10): 55s–63s.
Published: 01 January 1985
...John C. McGrath 1. The effects of varying [Ca 2+ ] o on the contraction of smooth muscle by different α-adrenoceptor agonists were examined on rat isolated anococcygeus muscle. Agonists were tested in the presence of various [Ca 2+ ] o or ‘Ca 2+ -re-addition curves’ were constructed. In some...
Articles
Clin Sci (Lond) (1984) 67 (6): 613–618.
Published: 01 December 1984
... Society and the Medical Research Society 1984 arterioles calcium forearm nitroprusside smooth muscle verapamil Clinical Science (1984)67, 613-618 613 Effect of small increments in plasma calcium concentration on the responsiveness of forearm resistance vessels to verapamil in normal subjects...
Articles
Clin Sci (Lond) (1982) 63 (s8): 31s–33s.
Published: 01 October 1982
... smooth muscle transmembrane potential vascular muscle CIinicalScience (1982) 6 3 . 3 1 ~ 3 3 ~ 31s Vascular smooth muscle membrane potential and a ouabain- like humoral factor in one-kidney, one-clip hypertension in rats M O T I L A L B. P A M N A N I , D A V I D R . H A R D E R , S T E P H E N J...
Articles
Clin Sci (Lond) (1982) 63 (s8): 83s–85s.
Published: 01 October 1982
...Yoshinori Kawaguchi; Kyuzo Aoki; Masahiko Yamamoto; Ken Hotta 1. Calcium reactivity of arterial smooth muscle and the effect of diltiazem (calcium antagonist) were investigated in helical strips of mesenteric arteries from 6-week-old male spontaneously hypertensive rats (SHR) and age-and sex...
Articles
Clin Sci (Lond) (1982) 63 (1): 33–42.
Published: 01 July 1982
... outside the normal range. 4. The abnormal pattern of response observed in the hypertensive group cannot be accounted for by structural changes in the vessels and strongly suggests a functional abnormality of the vascular smooth muscle. 16 7 1981 8 2 1982 © 1982 The Biochemical Society and...
Articles
Clin Sci (Lond) (1980) 59 (s6): 339s–342s.
Published: 01 December 1980
...R. Garcia; E. L. Schiffrin; G. Thibault; R. Boucher; J. Genest 1. The response of arterial smooth muscle to noradrenaline was studied in one-clip hypertensive rats with or without the contralateral/kidney and in normotensive rabbits. 2. Strips of aorta from one-kidney, one-clip hypertensive animals...
Articles
Clin Sci (Lond) (1980) 59 (s6): 207s–209s.
Published: 01 December 1980
...S. N. Orlov; Yu. V. Postnov 1. The ability of isolated membrane fractions of cardiomyocytes, aortic smooth muscle and erythrocytes from spontaneously hypertensive rats to bind calcium was investigated isotopically. 2. Plasma membranes of aortic smooth muscle and erythrocytes of spontaneously...
Articles
Clin Sci (Lond) (1980) 59 (s6): 327s–329s.
Published: 01 December 1980
... Society and the Medical Research Society 1980 hypertension proline smooth muscle sympathetic nervous system Clinical Science (1980) 59,327S-329S 327s Rapid onset of vascular wall protein synthesis with increase in lability of blood pressure in rabbits A. G. M A C L E A N , R . D . B E V A N...
Articles
Clin Sci Mol Med (1978) 55 (3): 235–240.
Published: 01 September 1978
... therapeutic action in man. Propranolol has non-specific inhibitory effects on vascular smooth muscle, which might contribute to its hypotensive activity at high concentrations, but oxprenolol has only slight peripheral effects that are probably therapeutically insignificant. 23 12 1977 12 4 1978...
Articles
Clin Sci Mol Med (1973) 45 (s1): 247s–250s.
Published: 01 August 1973
... AMP. © 1994 The Biochemical Society and the Medical Research Society 1994 angiotensin adenylcyclase phosphodiesterase cyclic AMP smooth muscle uterus Clinical Science and Molecular Medicine (1973) 45,247~250s. EFFECTS O F ANGIOTENSIN I1 O N ADENYLCYCLASE ACTIVITY, PHOSPHODIESTERASE...