... by Portland Press Limited 2015 We examined the usefulness of a three-compartment model for description of lactate kinetics using stable isotopically labelled lactate in humans. The main results showed that adrenaline increased lactate release from, and mitochondrial ex vivo respiration in, human...

... in this short-term (8 h) dose–response study. L -Arginine-HCl was continuously infused [intravenously (IV)] in three stepwise-increasing doses (33, 66 and 99 μmol·kg −1 ·h −1 ). Whole-body arginine-NO and protein metabolism were measured using stable isotope techniques, and baseline values were compared...

... cardiopulmonary bypass coronary artery bypass graft (CABG) fibrinogen muscle protein synthesis stable isotope Surgical trauma is accompanied by accelerated protein catabolism with mobilization of amino acids [ 1 ]. Following surgery, the rate of protein synthesis is reduced in skeletal muscle [ 2 – 4...

... with an attenuated acute-phase response. This indicates that altered arginine metabolism may be an important characteristic of the metabolic changes in cancer. amino acid arginine cancer metabolism nitric oxide stable isotope surgery SAP concentrations in plasma were measured using a sandwich ELISA...

... reaction undergoing laparoscopic cholecystectomy. Correspondence: Dr Hans Barle (email [email protected] ). 19 7 2005 23 8 2005 6 9 2005 6 9 2005 The Biochemical Society 2006 cholecystitis inflammation liver protein MS stable isotope synthesis rate...

... test (IVGTT) minimal model stable isotope The primary measure of the equivalence of the behaviour of the two tracers was the direct comparison of the plasma tracer concentrations [ 11 ]. For all 40 IVGTTs performed, the correlation between the mole fractions of the two tracers was extremely...

... and the assessment of protein synthesis was completed according to an identical protocol that applied for the pre-operative measurement. protein synthesis skeletal muscle stable isotope surgical trauma Muscle protein catabolism is a considerable clinical problem following surgical trauma. This muscle...

... stable isotope label. Ten volunteers (nine female, one male) aged 24-55 years were recruited from the Norwich area to take part in a free-living study. The study was conducted in the Human Nutrition Unit at the Institute of Food Research, Norwich, U.K., and involved feeding breakfast test meals...

...G.F. WATTS; D.C.F. CHAN; P.H.R. BARRETT; I.J. MARTINS; T.G. REDGRAVE We aimed to investigate the metabolism of chylomicron remnants in the postabsorptive state employing a new stable isotope breath test in centrally obese men without overt hyperlipidaemia. Groups of 12 centrally obese and 12 non...

..., it is difficult to interpret these in vitro findings. Therefore, an in vivo technique has been established for determination of the fractional protein synthesis rate, as an index of metabolic activity in human peripheral blood lymphocytes, by using a stable isotope technique. 2. The rate of protein synthesis...

... by fasting. 26 1 1994 11 7 1994 22 8 1994 © 1994 The Biochemical Society and the Medical Research Society 1994 euglycaemic clamp fasting glucose-induced thermogenesis lipolysis [I- 13 C]palmitate stable isotope Clinical Science (1994) 87, 697-706 (Printed in Great Britain...

... : control subjects, 0.018 ± 0.002 min −1 , alcoholic patients, 0.031 ± 0.006 min −1 ). 5. These data therefore demonstrate that kinetic studies using stable isotopes of Zn can provide novel information on exchangeable Zn pools in man, but provide no support for the possibility of an underlying Zn depletion...

... and the Medical Research Society 1992 erythrocyte inductively coupled plasma iron absorption mass spectrometry plasma volume stable isotope Clinical Science (1992) 83, 213-219 (Printed in Great Britain) 213 Absorption of nophaem iron in normal women measured by the incorporation of two stable...

... intravascular albumin mass pregnancy stable isotope whole-body protein turnover ClinicalScience (1991) 81,161-168 161 Albumin metabolism in fasted subjects during late pregnancy 0. SAMSON OLUFEMI*, PAUL G. WHITTAKER, DAVE HALLIDAYT AND TOM LIND University Department of Obstetrics and Gynaecology, Princess...

... with stable isotopes, [ 15 N 2 ]urea, [6- 2 H]glucose and [3- 13 C]alanine, was used. 3. The rate of appearance of glucose and urea in the plasma was rapidly reduced by the 17.7 μUmol min −1 kg −1 glucose infusion. 4. In contrast, during the glucose infusion there was an increased rate of appearance...