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Keywords: stem cell
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Articles
Clin Sci (Lond) (2018) 132 (17): 1977–1994.
Published: 14 September 2018
...Meg L. McFetridge; Mark P. Del Borgo; Marie-Isabel Aguilar; Sharon D. Ricardo Chronic kidney disease (CKD) is a major and growing public health concern with increasing incidence and prevalence worldwide. The therapeutic potential of stem cell therapy, including mesenchymal stem cells (MSCs...
Articles
Clin Sci (Lond) (2015) 128 (2): 81–93.
Published: 05 September 2014
... injury pericyte regeneration stem cell In the late 1800s, the French scientist Charles-Marie Benjamin Rouget described a population of contractile cells in the capillaries, which were named after him [ 1 ]. Fifty years later, Karl Wilhelm Zimmermann renamed them pericytes because they were...
Articles
Clin Sci (Lond) (2014) 127 (11): 615–634.
Published: 25 July 2014
... of this pathophysiological process frequently leads to a failure of its prevention in patients. For this reason, innovative protocols, for example based on local gene delivery, targeted inhibition of gene expression or stem-cell-mediated repair of injured vessels, are continuously tested in pre-clinical models of vascular...
Articles
Clin Sci (Lond) (2013) 125 (3): 109–119.
Published: 12 April 2013
... myocardial regeneration. Although initial investigation centred on the ability of injected stem cells to differentiate into cardiomyocytes, more recent studies have revealed that the functional benefits of cell therapy arise through several mechanisms of action that generally involve the potentiation...
Articles
Clin Sci (Lond) (2010) 119 (8): 303–311.
Published: 06 July 2010
... & Research Center ( http://www.nrrrc.missouri.edu ). The establishment of the mouse ESC (embryonic stem cell) [ 23 ], and later discovery that these cells permit precise homologous recombination [ 24 , 25 ], has enabled the targeted disruption of mouse genes of interest and the development of thousands...
Articles
Clin Sci (Lond) (2010) 118 (2): 87–97.
Published: 12 October 2009
...Michael D. McCall; Christian Toso; Emmanuel E. Baetge; A. M. James Shapiro With the already heightened demand placed on organ donation, stem cell therapy has become a tantalizing idea to provide glucose-responsive insulin-producing cells to Type 1 diabetic patients as an alternative to islet...
Articles
Clin Sci (Lond) (2009) 117 (10): 355–364.
Published: 07 September 2009
... use, distribution and reproduction in any medium, provided the original work is properly cited. androgen cardiovascular system endothelial progenitor cell endothelium gender oestrogen stem cell Cardiovascular risk gradients are primarily driven by gender: women of a reproductive...
Articles
Clin Sci (Lond) (2009) 116 (3): 191–203.
Published: 08 January 2009
..., cardiovascular development, hypertension, cellular metabolism, oxidative stress, stem cell proliferation, immune system regulation and cancer. Current knowledge of FoxO protein function combined with future studies should continue to lay the foundation for the successful translation of these transcription...
Articles
Clin Sci (Lond) (2008) 114 (2): 99–108.
Published: 11 December 2007
...Michael R. Loebinger; Susana Aguilar; Sam M. Janes There has been increasing excitement over the last few years with the suggestion that exogenous stem cells may offer new treatment options for a wide range of diseases. Within respiratory medicine, these cells have been shown to have the ability...
Articles
Clin Sci (Lond) (2006) 110 (1): 73–88.
Published: 12 December 2005
... Neuroprotective: caspase inhibitors, mitochondrial enhancers and glutamine receptor blockers. Strategies targeted at probable specific HD processes Gene therapy; aggregate inhibitors; HDAC inhibitors. Reparative strategies Transplantation repair with primary cells; transplantation repair with stem cells...
Articles
Clin Sci (Lond) (2005) 108 (1): 1–11.
Published: 15 December 2004
... androgen cancer therapy epithelial cell differentiation growth factor prostate cancer stem cell The incidence of prostate cancer has increased over the past decade and it is now the most common non-cutaneous malignancy in Europe and North America [ 1 ]. Radical prostatectomy and radiation...
Articles