.... ChAT tgm showed specific traits in a central nervous system (CNS) phenotype, including decreased response to restraint stress, less depressive-like and anxiety-like behaviours and anti-convulsive effects, all of which may benefit the heart. These phenotypes, induced by the activation of cardiac NNCCS...

... stress sensor that is important in maintaining intracellular homoeostasis during many kinds of stress challenges. In the present paper, we will review recent literature showing that AMPK functions far beyond its proposed energy sensor and regulator function. AMPK regulates ROS (reactive oxygen species...

... and fetal oxidative stress, as well as down-regulation of placental 11β-HSD (11β-hydroxysteroid dehydrogenase). Decreased placental 11β-HSD activity increases fetal exposure to maternal glucocorticoids, further increasing fetal oxidative stress. To explore the developmental origins of co-morbid hypertension...

...-reactive protein (CRP) heart rate variability inflammation stress Vagal efferent control of HR (heart rate) is an important index of adaptive neurocardiac regulation. Among patients with CAD (coronary artery disease), vagal HR control is well known to exert a cardioprotective effect [ 1...

... for diagnosis and treatment titration in chronic fatigue syndrome. depression homoeostasis immunology pain stress sympathetic nervous system 117Clinical Science (1999) 96, 117 125 (Printed in Great Britain) + H Y P O T H E S I S Chronic fatigue syndrome: a hypothesis focusing on the autonomic nervous...

...Keith N. Frayn; Christine M. Williams; Peter Arner coronary heart disease insulin resistance non-esterified fatty acids non-insulin-dependent diabetes obesity stress Clinical Science (1996) W, 243-253 (Printed in Great Britain) Editorial Review 243 Are increased plasma non-esterified...

...Luigi S. Brandi; Donatella Santoro; Andrea Natali; Fiorella Altomonte; Simona Baldi; Silvia Frascerra; Eleuterio Ferrannini 1. Stress is associated with a severe, yet reversible, form of insulin resistance. The aim of this study was to quantify the kinetics of insulin action (sensitivity...

... and we conclude that they are related to hypoglycaemia-induced disorders of plasma neurotransmitters, rather than to hypoglycaemia per se. We postulate that an uncoping stress situation (type I and II patients) and depression (type III patients) underlie the physiopathological mechanisms. 28 11...

..., and that this response is of low naloxone sensitivity. 17 10 1988 25 10 1988 © 1989 The Biochemical Society and the Medical Research Society 1989 adrenaline adrenocorticotrophin catecholamines cortisol naloxone noradrenaline opioids stress Clinical Science (1989) 76,625-630 625...

... glucagon physiological models stress Clinical Science (1988) 74, 539-545 539 Increased hepatic amino nitrogen conversion after elective cholecystectomy in man HANS HEINDORFF HENDRIK VILSTRUP*, DITLEV BUCHER3, PER BILLESBOLLE' AND VIBEKE THYGESEN' 'Department of Surgery D, Herlev University Hospital...

... 21 5 1982 © 1982 The Biochemical Society and the Medical Research Society 1982 corticotropin Cortisol β-endorphin/β-lipotropin ischaemic pain γ-lipotropin pro-opiocortin stress Clinical Science (1982) 63,397-400 397 The response of plasma immunoreactive adrenocorticotropin, D...

... pathogenesis stress vascular reactivity Clinical Science (1982) 63,371s-374s 371s Different haemodynamic reaction patterns during noise exposure in normotensive subjects with and without heredity for essential hypertension L. A N D R B N , S. P I R O S , L. H A N S S O N , H . H E R L I T Z A N D 0. J O N...

... 1982 adrenalaine cortisol growth hormone haemodynamics hypertension noise noradrenaline prolactin stress Clinical Science (1982) 62,137-141 137 Effect of noise on blood pressure and stress hormones L. ANDRfiN, G. LINDSTEDT, M. BJORKMAN, K. 0. BORG A N D L. HANSSON Hypertension Section...

... disappeared after 5 min of quiet rest at 40 dBA. Key words: P-adrenoceptor blockade, blood pressure, essential hypertension, haemodynamics, noise, stress. Introduction The pathogenesis of essential hypertension is complex and still not fully understood. Hereditary factors are undoubtedly of importance 11...

... sodium stress CIinicalScience (1981) 61,2Ss-27s 25 s Intralymphocytic sodium concentration as an index of response to stress and exercise in young subjects with borderline hypertension E. A M B R O S I O N I , F. V . C O S T A , L. M O N T E B U G N O L I , C . B O R G H I A N D B . M A G N A N I...

...D. N. Brindley © 1981 The Biochemical Society and the Medical Research Society 1981 atherosclerosis diabetes diet ethanol fatty liver fructose glucocorticoids insulin lipid metabolism lipoprotein lipase lipoproteins obesity l-α-phosphatidate phosphohydrolase sorbitol stress...

... and/or of an increase of potassium intake from 80 to 200 mmol/day over a 2 week period, on blood pressure, plasma noradrenaline, adrenaline, vasopressin, renin and aldosterone, were measured both at rest and after mental stress. The effects of graded infusion of noradrenaline on blood pressure and heart rate were also...

.... 3. Performance was similar after β-adrenoreceptor-blocking agents or placebo. 4. Blood pressure response to stress persisted after administration of the blocking agents. © 1979 The Biochemical Society and the Medical Research Society 1979 metoprolol propranolol stress Clinical Science...

...H. Ignatowska-S̀witalska; T. Klonowicz; T. Feltynowski 1. The influence of mental stress, 30 min Kraepelin's arithmetic test under noise on the plasma concentration and urinary excretion of prostaglandin (PG) F 2α was studied in patients with essential hypertension and in healthy subjects. 2...

... of plasma tryptophan in the free state were more marked than absolute increases of free tryptophan. 2. Plasma tyrosine fell slightly and plasma phenylalanine and cortisol were unaffected. 3. It is suggested that catecholamine release could lead to abnormalities of tryptophan disposition in stress...