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1-20 of 20
Keywords: subcellular fractionation
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Articles
Mitochondrial Protein Content and in Vivo Synthesis Rates in Skeletal Muscle from Critically Ill Rats
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (4): 475–481.
Published: 01 October 1996
... and myofibrillar protein) were obtained during the fractionation procedure. Key words cytochrome c oxidase, fatiguability, flooding dose, muscle wasting, subcellular fractionation, zymosan. Abbreviations: FSR, fractional synthesis rate; SA, specific activity. Correspondem Dr 0. Rooyackers. Endocrine Research Unit...
Articles
Electron paramagnetic resonance spectroscopy of stable free radicals in the liver compared with ultrastructural and functional damage in a rat model of alcohol- and iron-overload
Available to PurchaseGraham P. Butcher, Nigel Deighton, Roger M. Batt, Boliang Ding, Susan Haywood, John Hoffman, Malcolm J. Jackson, Martyn C. R. Symons, Jonathan M. Rhodes
Journal:
Clinical Science
Clin Sci (Lond) (1993) 84 (3): 339–348.
Published: 01 March 1993
... The Biochemical Society and the Medical Research Society 1993 alcohol free radical iron liver mitochondria peroxisome electron paramagnetic resonance spectroscopy subcellular fractionation Clinical Science (1993) 84, 339-348 (Printed in Great Britain) 339 Electron paramagnetic resonance...
Articles
Further studies on the activity and subcellular distribution of alanine: Glyoxylate aminotransferase in the livers of patients with primary hyperoxaluria type 1
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1988) 75 (3): 315–322.
Published: 01 September 1988
... with an undefined form of primary hyperoxaluria (possibly oxalate hyperabsorption) had normal AGT levels. The livers of a very mild PH1-type variant and a PH1 heterozygote had intermediate levels of AGT activity. 4. Subcellular fractionation of four PH1 livers by sucrose gradient isopycnic centrifugation...
Articles
Subcellular Fractionation Studies on Hepatic Tissue from a Patient with Pompe's Disease (Type II Glycogen-Storage Disease)
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1980) 59 (1): 7–12.
Published: 01 July 1980
...T. J. Peters; W. Jenkins; V. Dubowitz 1. An homogenate of liver biopsy taken from a patient with Pompe's disease (type II glycogen-storage disease) was analysed by enzyme microassay and subcellular fractionation by sucrose-density-gradient centrifugation. 2. A strikingly low activity of lysosomal...
Articles
Sequential Enzyme and Subcellular Fractionation Studies on Jejunal Biopsy Specimens from Patients with Post-Infective Tropical Malabsorption
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1979) 56 (5): 479–486.
Published: 01 May 1979
... 8 1978 15 12 1978 © 1979 The Biochemical Society and the Medical Research Society 1979 basal—lateral membrane brush borders cytosol endoplasmic reticulum enzymes giardiasis lysosomes mitochondria subcellular fractionation tropical malabsorption Clinical Science (1979...
Articles
Subcellular Distribution of Radio-Labelled Iron during Intestinal Absorption in Guinea-Pig Enterocytes with Special Reference to the Mitochondrial Localization of the Iron
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1979) 56 (2): 179–188.
Published: 01 February 1979
...J. M. P. Hopkins; T. J. Peters 1. 59 Fe-labelled ferric chloride was introduced into tied loops of guinea-pig jejunum. 2. After 5–30 min the loop was removed, the enterocytes were isolated, homogenized and subjected to analytical subcellular fractionation. 3. Uptake of 59 Fe was extremely rapid...
Articles
Analytical Subcellular Fractionation Studies on Different Cell Types Isolated from Normal Rat Liver
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (5): 423–427.
Published: 01 November 1978
... organelles were determined in the isolated cell homogenates and compared with whole liver homogenates. 3. The cells were disrupted and the extracts subjected to analytical subcellular fractionation by sucrose-density-gradient centrifugation. Lysosomal integrity was determined by assaying latent β- N...
Articles
The Effects of Prednisolone on the Rat Enterocyte at a Subcellular Level
Available to Purchase
Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (5): 435–443.
Published: 01 November 1978
... The Biochemical Society and the Medical Research Society 1978 brush border enterocyte ileum intestine jejunum steroid subcellular fractionation Clinical Science and Molecular Medicine (1 978) 55,435-443 The effects of prednisolone on the rat enterocyte at a subcellular level R . M. B A T T , G. W E...
Articles
Changes in Hepatic Enzymes and Organelles in Alcoholic Liver Disease
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (4): 383–389.
Published: 01 October 1978
... Society 1978 alcoholic liver disease enzymes ethanol lysosomes microsomes mitochondria subcellular fractionation plasma membrane Clinical Science and Molecular Medicine (1978) 55, 383-389 Changes in hepatic enzymes and organelles in alcoholic liver disease C A R O L A. S E Y M O U R * A N...
Articles
Analytical Subcellular Fractionation of Jejunal Biopsy Specimens: Enzyme Activities, Organelle Pathology and Response to Gluten Withdrawal in Patients with Coeliac Disease
Available to Purchase
Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (3): 285–292.
Published: 01 September 1978
...T. J. Peters; P. E. Jones; G. Wells 1. Portions of jejunal biopsy specimens from patients with coeliac disease were homogenized in isotonic sucrose solution and subjected to analytical subcellular fractionation by sucrose-density-gradient centrifugation. 2. The activities and distribution of marker...
Articles
Analytical Subcellular Fractionation of Jejunal Biopsy Specimens: Enzyme Activities, Organelle Pathology and Response to Corticosteroids in Patients with Non-Responsive Coeliac Disease
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (3): 293–300.
Published: 01 September 1978
...T.J. Peters; P.E. Jones; W.J. Jenkins; Gill Wells 1. Jejunal biopsies from five patients with non-responsive coeliac disease have been subjected to analytical subcellular fractionation and enzymic microassay in order to compare the organelle pathology of this group with untreated but gluten...
Articles
Analytical Subcellular Fractionation Studies on Enterocytes from the Jejunum and Ileum of the Rat and Some Properties of Brush-Border Alkaline Phosphatase
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (2): 157–165.
Published: 01 August 1978
... fragility. 12 10 1977 13 3 1978 © 1978 The Biochemical Society and the Medical Research Society 1978 alkaline phosphatase brush border enterocyte ileum intestine jejunum subcellular fractionation Clinical Science and Molecular Medicine (1978) 55,157-165 Analytical subcellular...
Articles
Subcellular Localization of Enterokinase in Human Duodenal Mucosa
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Journal:
Clinical Science
Clin Sci Mol Med (1977) 53 (6): 551–562.
Published: 01 December 1977
...R. W. Lobley; Ruth Franks; R. Holmes 1. Specimens of human duodenal mucosa were obtained at duodenotomy. Superficial mucosal scrapings were homogenized in isotonic sucrose solution and fractionated by differential centrifugation. The distribution of organelles among the subcellular fractions...
Articles
Analytical Subcellular Fractionation of Guinea-Pig Myocardium
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Journal:
Clinical Science
Clin Sci Mol Med (1977) 53 (1): 63–74.
Published: 01 July 1977
... mitochondria myocardium sarcolemma subcellular fractionation Clinical Science and Molecular Medicine (1917) 53, 63-74. Analytical subcellular fractionation of guinea-pig myocardium F. J. BLOOMFIELD, G. WELLS, E . WELMAN AND T. J . PETERS Department of Medicine, Royal Postgraduate Medical School, London...
Articles
Analytical Subcellular Fractionation of Human Granulocytes with Special Reference to the Localization of Enzymes Involved in Microbicidal Mechanisms
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Journal:
Clinical Science
Clin Sci Mol Med (1977) 52 (4): 429–442.
Published: 01 April 1977
...A. W. Segal; T. J. Peters 1. Granulocytes were isolated from 40–400 ml of human blood, disrupted and subjected to analytical subcellular fractionation by centrifugation on sucrose density gradients. 2. The principal subcellular organelles, characterized by their respective marker enzymes, were...
Articles
Lysosomal Changes in Liver Tissue from Patients with the Dubin—Johnson—Sprinz Syndrome
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Journal:
Clinical Science
Clin Sci Mol Med (1977) 52 (3): 241–248.
Published: 01 March 1977
...Carol A. Seymour; G. Neale; T. J. Peters 1. Clinical, morphological and biochemical data, including data obtained from the application of subcellular fractionation techniques to liver biopsy specimens, are presented for two patients with the Dubin-Johnson-Sprinz (DJS) syndrome. 2. Subcellular...
Articles
Analytical Subcellular Fractionation of Jejunal Biopsy Specimens: Methodology and Characterization of the Organelles in Normal Tissue
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Journal:
Clinical Science
Clin Sci Mol Med (1976) 51 (6): 557–574.
Published: 01 December 1976
... membrane subcellular fractionation jejunum Clinical Science and Molecular Medicine (1976) 51, 557-574. Analytical subcellular fractionation of jejunal biopsy specimens : methodology and characterization of the organelles in normal tissue T. J. PETERS Department of Medicine, Royal Postgraduate Medical...
Articles
Tissue and Hepatic Subcellular Distribution of Liposomes Containing Bleomycin after Intravenous Administration to Patients with Neoplasms
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Journal:
Clinical Science
Clin Sci Mol Med (1976) 51 (4): 421–425.
Published: 01 October 1976
... of liposomes revealed particles morphologically indistinguishable from liposomes in hepatoma cells and hepatocytes. 30 12 1975 © 1976 The Biochemical Society and the Medical Research Society 1976 bleomycin cancer hepatoma liposomes liver secondary carcinoma subcellular fractionation...
Articles
Analytical Subcellular Fractionation Studies on Rat Liver and on Isolated Jejunal Enterocytes with Special Reference to the Separation of Lysosomes, Peroxisomes and Mitochondria
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Journal:
Clinical Science
Clin Sci Mol Med (1976) 50 (5): 355–366.
Published: 01 May 1976
... and Molecular Medicine (1976) 50, 355-366. Analytical subcellular fractionation studies on rat liver and on isolated jejunal enterocytes with special reference to the separation of lysosomes, peroxisomes and mitochondria T. J . PETERS AND H. SHIO Royal Postgraduate Medical School, London, and The Rockefeller...
Articles
Analytical Subcellular Fractionation of Human Granulocytes with Reference to the Localization of Vitamin B 12 -Binding Proteins
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Journal:
Clinical Science
Clin Sci Mol Med (1975) 49 (2): 171–182.
Published: 01 August 1975
... The Biochemical Society and the Medical Research Society 1975 granulocytes leucocytes lysosomes microsomes mitochondria plasma membranes subcellular fractionation vitamin B 12 vitamin B 12 -binding proteins Clinical Science and Molecular Medicine (1975) 49, 171-1 82 Analytical subcellular...