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Keywords: sulphation
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Journal:
Clinical Science
Clin Sci (Lond) (1992) 83 (5): 623–626.
Published: 01 November 1992
...A. H. Raouf; H. H. Tsai; N. Parker; J. Hoffman; R. J. Walker; Jonathan M. Rhodes 1. Normal colonic mucin is heavily sulphated and this increases its resistance to degradation by bacterial enzymes. Any defect in mucus sulphation could therefore be important in the pathogenesis of ulcerative colitis...