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1-7 of 7
Keywords: superoxide anion
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2012) 123 (8): 509–518.
Published: 29 June 2012
... increased NO • production as expected. Intriguingly, endothelial O 2 •− (superoxide anion) production was up-regulated by DES in vitro and in vivo , which was, however, attenuated by the ER (oestrogen receptor) antagonist ICI 182780, the XO (xanthine oxidase) inhibitor oxypurinol or the NOX (NADPH oxidase...
Articles
Alvaro Yogi, Glaucia E. Callera, Ulisses V. Hipólito, Catiane R. Silva, Rhian M. Touyz, Carlos R. Tirapelli
Journal:
Clinical Science
Clin Sci (Lond) (2010) 118 (11): 657–668.
Published: 09 March 2010
.../l) increased ethanol-induced contraction. Tiron [O 2 − (superoxide anion) scavenger, 1 mmol/l] and catalase (H 2 O 2 scavenger, 300 units/ml) reduced ethanol-induced contraction to a similar extent in both endothelium-intact and denuded rings. Similarly, indomethacin (non-selective COX inhibitor...
Articles
José M. González, Beatriz Somoza, M. Victoria Conde, Maria S. Fernández-Alfonso, M. Carmen González, Silvia M. Arribas
Journal:
Clinical Science
Clin Sci (Lond) (2008) 114 (10): 651–659.
Published: 14 April 2008
... development. Young pre-hypertensive and adult fully hypertensive SHRs and age-matched Wistar–Kyoto rat controls were used. The contribution of basal vasoactive factors to resting tone was studied in middle cerebral arteries with pressure myography. Basal NO and O 2 − (superoxide anion) availability were...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2008) 114 (3): 173–182.
Published: 08 January 2008
... the cardiovascular system, a family of multisubunit NADPH oxidases appears to be a predominant contributor of superoxide anion. Recent findings suggest a significant role of the genetic background in NADPH oxidase regulation. Common genetic polymorphisms within the promoter and exonic sequences of CYBA , the gene...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2006) 111 (1): 1–20.
Published: 14 June 2006
...Mark T. Quinn; Mary Cloud B. Ammons; Frank R. DeLeo The NADPH oxidase was originally identified as a key component of human innate host defence. In phagocytes, this enzyme complex is activated to produce superoxide anion and other secondarily derived ROS (reactive oxygen species), which promote...
Articles
Marta ESCRIBANO-BURGOS, Antonio LÓPEZ-FARRÉ, María del MAR GONZÁLEZ, Carlos MACAYA, Antonio GARCÍA-MÉNDEZ, Petra J. MATEOS-CÁCERES, Sergio ALONSO-ORGAZ, Carolina CARRASCO, Luis A. RICO, Juan Carlos PORRES CUBERO
Journal:
Clinical Science
Clin Sci (Lond) (2005) 108 (1): 85–91.
Published: 15 December 2004
.... An alteration of the NO (nitric oxide)-dependent vasorelaxation has been defined as endothelial dysfunction. Endothelial dysfunction has been associated with the presence of superoxide anion and with a reduction in the expression of the eNOS (endothelial NO synthase). A concentration of CRP similar...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1999) 97 (6): 625–631.
Published: 29 October 1999
...Mercedes FERRER; Nuria TEJERA; Jesús MARÍN; Gloria BALFAGÓN The aim of the present study was to assess the role of superoxide anions in the relaxation induced by acetylcholine (ACh) in aortic segments from male rats, and to investigate if their production is altered by sex hormone deprivation...