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Keywords: superoxide anion
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Clin Sci (Lond) (2010) 118 (11): 657–668.
Published: 09 March 2010
.../l) increased ethanol-induced contraction. Tiron [O 2 − (superoxide anion) scavenger, 1 mmol/l] and catalase (H 2 O 2 scavenger, 300 units/ml) reduced ethanol-induced contraction to a similar extent in both endothelium-intact and denuded rings. Similarly, indomethacin (non-selective COX inhibitor...
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Clin Sci (Lond) (2008) 114 (3): 173–182.
Published: 08 January 2008
... the cardiovascular system, a family of multisubunit NADPH oxidases appears to be a predominant contributor of superoxide anion. Recent findings suggest a significant role of the genetic background in NADPH oxidase regulation. Common genetic polymorphisms within the promoter and exonic sequences of CYBA , the gene...
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Clin Sci (Lond) (2006) 111 (1): 1–20.
Published: 14 June 2006
...Mark T. Quinn; Mary Cloud B. Ammons; Frank R. DeLeo The NADPH oxidase was originally identified as a key component of human innate host defence. In phagocytes, this enzyme complex is activated to produce superoxide anion and other secondarily derived ROS (reactive oxygen species), which promote...
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Clin Sci (Lond) (2005) 108 (1): 85–91.
Published: 15 December 2004
.... An alteration of the NO (nitric oxide)-dependent vasorelaxation has been defined as endothelial dysfunction. Endothelial dysfunction has been associated with the presence of superoxide anion and with a reduction in the expression of the eNOS (endothelial NO synthase). A concentration of CRP similar...
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