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Clin Sci (Lond) (2008) 114 (9): 603–610.
Published: 02 April 2008
... by suboptimal nutritional regimens or insensitive clinical methods. The aim of the present study was therefore to evaluate the effects on the initiation of translation of skeletal muscle proteins by standard overnight TPN. A total of 12 patients who underwent standard surgery were included. TPN was provided...
Includes: Supplementary data
Yvonne L. J. Vissers, Maarten F. von Meyenfeldt, Yvette C. Luiking, Cornelis H. C. Dejong, Wim A. Buurman, Nicolaas E. P. Deutz
Clin Sci (Lond) (2007) 112 (10): 527–532.
Published: 12 April 2007
... with an attenuated acute-phase response. This indicates that altered arginine metabolism may be an important characteristic of the metabolic changes in cancer. amino acid arginine cancer metabolism nitric oxide stable isotope surgery We have described recently [ 1 ] that patients with malignant...
Clin Sci (Lond) (2005) 108 (5): 413–424.
Published: 22 April 2005
...Daniel D. MELLEY; Timothy W. EVANS; Gregory J. QUINLAN SIRS (systemic inflammatory response syndrome) may result from a wide variety of non-infective insults. Surgery is a recognized cause of SIRS, the onset of which can have adverse prognostic significance. Neutrophil activation is a key...
Joan LÓPEZ-HELLÍN, Ricardo GONZALO, Mónica TEJEDA, Montserrat CARRASCAL, Maya R. VILÀ, Joaquín ABIÁN, Elena GARCÍA-ARUMÍ
Clin Sci (Lond) (2005) 108 (2): 167–178.
Published: 21 January 2005
... and their role in the stress response. Our aim was to study how individual proteins in liver and muscle are altered by abdominal surgery. Changes produced in mRNA and proteins by abdominal surgery were studied in rats using RAP (random arbitrary priming)-PCR, to investigate mRNA alterations, and standard...
Michael J. O'LEARY, Colin N. FERGUSON, Michael J. RENNIE, Charles J. HINDS, John H. COAKLEY, Victor R. PREEDY
Clin Sci (Lond) (2001) 101 (3): 295–304.
Published: 15 August 2001
... concentrations. Male Wistar rats underwent caecal ligation and puncture (CLP) or sham operation, with starvation, and were killed 24, 72 or 96 h later. A group of non-operated animals were killed at the time of surgery. Protein synthesis was determined using a flooding dose of l -[4- 3 H] phenylalanine...
Clin Sci (Lond) (2000) 98 (1): 71–79.
Published: 23 November 1999
...G. M. HALL; D. PEERBHOY; A. SHENKIN; C. J. R. PARKER; P. SALMON Changes in circulating levels of catecholamines, cortisol, glucose, interleukin-6 and C-reactive protein and in the leucocyte count were investigated for 7 days after surgery in 158 patients undergoing hip or knee arthroplasty. We...
Pia Essén, Margaret A. McNurlan, Anders Thorell, Inga Tjäder, Giuseppe Caso, Susan E. Anderson, Jan Wernerman, Peter J. Garlick
Clin Sci (Lond) (1996) 91 (1): 99–106.
Published: 01 July 1996
... > 0.02), irrespective of postoperative total parenteral nutrition or preoperative glucose infusion. In contrast to surgery, insulin did not stimulate protein synthesis in peripheral mononuclear leucocytes. 22 3 1996 28 3 1996 © 1996 The Biochemical Society and the Medical Research...
Clin Sci (Lond) (1995) 89 (4): 383–388.
Published: 01 October 1995
...Peter W. Emery; Peter Sanderson 1. The healing of an abdominal muscle wound after surgery is associated with a considerable increase in the rate of protein synthesis. We have investigated whether this increase in protein synthesis is affected by chronic undernutrition, and whether this causes...
Clin Sci (Lond) (1995) 88 (4): 479–484.
Published: 01 April 1995
... reflect the capacity for protein synthesis. 2. Patients with weight loss due to cancer ( n = 6) were compared with metabolically healthy patients before elective surgery ( n = 7). Alkali-soluble protein/DNA and RNA/DNA ratios in the weight loss group were 248 (14) g/g and 1.3 (0.1) g/g respectively...
Clin Sci (Lond) (1989) 76 (3): 317–322.
Published: 01 March 1989
... between glycogenesis and lipid synthesis after liver resection: specific effects of liver regeneration, coupled with non-specific effects of surgery MARK J. HOLNESS, PAUL S. SCHOFIELD AND MARY C. SUGDEN Department of Chemical Pathology, The London Hospital Medical College, London (Received 21 April128...
Clin Sci (Lond) (1988) 74 (1): 107–112.
Published: 01 January 1988
...Timothy J. French; Mark J. Holness; Anthony W. Goode; Mary C. Sugden 1. The work utilized a model of uncomplicated abdominal surgery (laparotomy under ether anaesthesia) to delineate the effects of abdominal trauma on glucose homoeostasis in the fed rat. 2. Regulation of glucose production...
J. M. Ritter, G. Hamilton, S. E. Barrow, D. J. Heavey, N. E. Hickling, K. M. Taylor, K. E. F. Hobbs, C. T. Dollery
Clin Sci (Lond) (1986) 71 (6): 743–747.
Published: 01 December 1986
... ) is the stable hydrolysis product of PGI 2 and was measured in plasma from patients undergoing hepatic or cardiac surgery and in unoperated patients with vascular and hepatic disease, using gas chromatography/mass spectrometry. 2. Blood obtained simultaneously from portal and peripheral veins, during emergency...
Clin Sci (Lond) (1983) 64 (1): 109–111.
Published: 01 January 1983
...G. M. Hall; Celine Traynor; J. L. Paterson 1. Changes in liver glycogen and glycolytic intermediates were determined in ten patients undergoing abdominal surgery for carcinoma of the colon. 2. One hour of surgery resulted in a 19% decrease in liver glycogen, together with an increase in hepatic...
K. J. Foster, K. G. M. M. Alberti, C. Binder, Leslie Hinks, S. Karran, Patricia Smythe, S. Talbot, D. Turnell, H. Ørskov
Clin Sci (Lond) (1980) 58 (6): 507–515.
Published: 01 June 1980
... and is apparently unrelated to changes in ketone bodies and insulin. 13 3 1979 31 10 1979 © 1980 The Biochemical Society and the Medical Research Society 1980 alanine amino acids glucagon glucose insulin ketone bodies 3-methylhistidine nitrogen surgery Clinical Science (1980...
Clin Sci Mol Med (1973) 45 (s1): 315s–316s.
Published: 01 August 1973
... hypertension surgery Clinical Science and Molecular Medicine (1973) 45, 315s-316s. IMPROVED TECHNIQUE FOR AORTO-RENAL RECONSTRUCTION: A HAEMODYNAMIC APPROACH U. R U B E R T I , A. VEGETO A N D E. M A L A N Department of Surgery, University of Milan, Italy SUMMARY 1. An improved method of aorto-renal...