... prognosis survival • DM is very common in patients with liver cirrhosis, and may increase mortality, either by accelerating deterioration of liver function, or by predisposing to serious infections, such as SBP. • In the present study, the presence of DM at baseline was associated...

... (odds ratios) of RRM2-high for distant metastases were 2.06 [95% CI (confidence interval), 1.01–4.30] and 5.89 (95% CI, 1.51–39.13) in the COH and ZJU sets respectively. The Kaplan–Meier analysis displayed that high expression of RRM2 had a negative impact on the OS (overall survival) and PFS (progress...

... MET would improve cardiac function and survival also in non-diabetic HF. Volume-overload HF was induced in male Wistar rats by creating ACF (aortocaval fistula). Animals were randomized to placebo/MET (300 mg·kg −1 of body weight·day −1 , 0.5% in food) groups and underwent assessment of metabolism...

...Bing Dai; Yawei Liu; Changlin Mei; Lili Fu; Xishan Xiong; Yan Zhang; Xuefei Shen; Zhenhao Hua Although pioglitazone, a PPAR-γ (peroxisome-proliferator-activated receptor-γ) agonist, has been shown to prolong survival in two rapidly progressive pkd1 (polycystic kidney disease 1)-knockout mice models...

... is an important survival mechanism. However, the occurrence of autophagic structures in dying cells of different organisms has led to the hypothesis that autophagy may also have a causative role in stress-induced cell death. The identification within the last decade of a full set of genes essential for autophagy...

... to six missing specimens over the whole period. All patients received standard parenteral nutrition [1700 kcal/day (where 1 kcal≈4.184 kJ) and 100 g of amino acids/day] after the end of hypodynamic shock. kynurenine indoleamine 2,3-dioxygenase (IDO) survival tryptophan trauma ©...

... by loss of liver function for which no effective therapies are available. Hepatocytes are well equipped with protective mechanisms to prevent cell death. As long as these protective mechanisms can be activated, the balance will be in favour of cell survival. However, the balance between cell survival...

... and cell death simultaneously, whereas LPA is a survival factor. We speculate that PDGF and LPA may play important roles in the progression or exacerbation of proliferative glomerulonephritis. Correspondence: Dr Chiyoko N. Inoue, Department of Pediatrics, Japanese Red Cross Sendai Hospital 43–3...

...% corn oil. After 4 weeks, survival of mice ( n = 12/treatment group) injected intraperitoneally with 2 × 10 6 colony forming units of live Listeria monocytogenes was determined. In a second study, bacterial clearance from the liver and spleen at 2, 4 and 7 days post-challenge was determined ( n = 8...