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Keywords: synaptic plasticity
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2017) 131 (2): 123–138.
Published: 23 December 2016
...Veronica Begni; Marco Andrea Riva; Annamaria Cattaneo Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays a key role in the central nervous system, promoting synaptic plasticity, neurogenesis and neuroprotection. The BDNF gene structure is very complex and consists of multiple 5...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2017) 131 (1): 13–23.
Published: 01 December 2016
... in the hippocampus [ 50 ]. Many effects of BDNF on synaptic structure and connectivity are governed by neuronal activity [ 51 ]. In addition to phosphorylation of TrkB, there are several mechanisms that can account for BDNF's effects upon synaptic plasticity. One important regulatory mechanism is the processing...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2016) 130 (14): 1137–1146.
Published: 01 June 2016
...Hongmei Shen; Zheng Li The identification and functional delineation of miRNAs (a class of small non-coding RNAs) have added a new layer of complexity to our understanding of the molecular mechanisms underlying synaptic plasticity. Genome-wide association studies in conjunction with investigations...
