...Mamoru Satoh; Takahito Nasu; Yuji Takahashi; Takuya Osaki; Sho Hitomi; Yoshihiro Morino; Motoyuki Nakamura Telomeric repeat binding factor (TRF) 2 (TRF2) plays an important role in telomere maintenance. miR-23a may directly inhibit TRF2 expression, thereby, inducing telomere shortening and cellular...

... therapeutic agent for the treatment of coronary atherosclerosis. The present review summarizes the cellular and molecular mechanism of statins against coronary atherosclerosis. atherosclerosis endothelial progenitor cells miRNA SIRT-1 telomere toll-like receptor 4 A recent study has reported...

... aging biological age congitive age longevity telomere telomere length The review by Zhu et al. [ 1 ] appearing in Clinical Science earlier this year is one of several excellent recent review papers on telomeres and aging that, taken together, point to the importance of bridging the gap...

.... Despite the remarkable progress made during the last two decades, our understanding of the biology of aging remains incomplete. Telomere biology has recently emerged as an important player in the aging and disease process. Telomerase function is also regulated by genetic, epigenetic and environmental...