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Keywords: teprotide
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Articles
Excitatory Effect of Converting Enzyme Inhibitors on Efferent Sympathetic Postganglionic Nerve Activity to the Kidney in the Rat
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (s7): 223s–225s.
Published: 01 December 1981
... nerve activity from the right renal nerves were recorded in anaesthetized, spontaneously breathing, non diuretic rats, either with an intact spinal cord or with a spinal cord transected at the T6 level, before, during and after intravenous injections of 0.5–1.0 mg/kg of teprotide or captopril. 3. After...
Articles
Complex Competitive and Non-Competitive Inhibition of Rat Lung Angiotensin-Converting Enzyme by Inhibitors Containing Thiol Groups: Captopril and SA 446
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (s7): 277s–280s.
Published: 01 December 1981
.... Teprotide was the least potent inhibitor with a K 1 of near 20 nmol/l whereas captopril (SQ 14 225) and SA 446 were both approximately 10 times and MK 421 approximately 20 times more potent. 5. Two inhibitors which lacked thiol groups [teprotide or SQ 20 881 and N -(1- S -1-carboxy-3-phenylpropyl)- l -Ala...