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Keywords: testosterone
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Articles
Clin Sci (Lond) (2016) 130 (14): 1147–1163.
Published: 01 June 2016
... inequalities oestrogen sex testosterone In My Fair Lady (1956), Professor Higgins asked this question rhetorically from an absurdly biased, male point of view. This classic Broadway musical was based on George Bernard Shaw's Pygmalion (1913), a theatrical play reflecting the old-fashioned views...
Articles
Clin Sci (Lond) (2015) 129 (1): 39–48.
Published: 01 April 2015
...Andreia Z. Chignalia; Maria Aparecida Oliveira; Victor Debbas; Randal O. Dull; Francisco R.M. Laurindo; Rhian M. Touyz; Maria Helena C. Carvalho; Zuleica B. Fortes; Rita C. Tostes The mechanisms whereby testosterone increases cardiovascular risk are not clarified. However, oxidative stress...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2008) 114 (2): 85–97.
Published: 11 December 2007
...-oestradiol sex testosterone Figure 1 Vascular ET system ET-1 synthesis is controlled via regulation of gene transcription and/or ECE activity and its release occurs mostly abluminally. ET-1 acts on ET A and ET B smooth muscle receptors to induce vasoconstrictor, pro-oxidant, pro-inflammatory...
Articles
Clin Sci (Lond) (2006) 111 (4): 251–252.
Published: 13 September 2006
... to promote increases in blood pressure and compromise renal function. In the present issue of Clinical Science , Malkin and co-workers show that testosterone replacement impairs vascular reactivity in men with androgen deficiency. These studies may shed light on the functional and therapeutic significance...
Articles
Clin Sci (Lond) (2006) 111 (4): 265–274.
Published: 13 September 2006
...Christopher J. Malkin; Richard D. Jones; T. Hugh Jones; Kevin S. Channer Testosterone is reported to have an acute vasodilating action in vitro , an effect that may impart a favourable haemodynamic response in patients with chronic heart failure. However, the effect of chronic testosterone exposure...
Articles
Clin Sci (Lond) (2004) 107 (2): 149–158.
Published: 27 July 2004
...Richard D. JONES; Kate M. ENGLISH; T. Hugh JONES; Kevin S. CHANNER Testosterone decreases myocardial ischaemia in men with coronary artery disease via a coronary vasodilatory action. However, long-term therapy may increase the risk of prostatic carcinoma via activation of the nuclear AR (androgen...
Articles
Clin Sci (Lond) (2003) 105 (6): 663–669.
Published: 01 December 2003
...K. J. ELLIOTT; N. T. CABLE; T. REILLY; M. J. DIVER To investigate the effect of changes in sex hormone concentration on muscle strength and the bioavailability of 17-β oestradiol (oestradiol) and testosterone, seven eumenorrheic females were tested during two phases of the menstrual cycle. Maximum...
Articles
Clin Sci (Lond) (2002) 103 (5): 487–491.
Published: 11 October 2002
... controls by time since menopause and by body mass index. Serum levels of androstenedione and total testosterone were measured by radioimmunoassays. Free testosterone was calculated from total testosterone, immunoassayed sex hormone-binding globulin and albumin. The mean±S.D. serum level of androstenedione...
Articles
Clin Sci (Lond) (2001) 100 (6): 661–665.
Published: 14 May 2001
... the effects of cigarette smoking on the levels of total and free testosterone have reported conflicting findings, but there has been no accurate assessment of the effects of cigarette smoking on the levels of bioavailable testosterone [not bound to sex hormone-binding globulin (SHBG)]. We attempted...
Articles
Clin Sci (Lond) (2000) 99 (1): 77–82.
Published: 15 June 2000
...Kate M. ENGLISH; Richard D. JONES; Hugh T. JONES; Alyn H. MORICE; Kevin S. CHANNER This study was performed to examine whether aging affects the vasodilatory effects of testosterone in the coronary arteries of male rats. Isolated coronary arteries from young mature (3–4 months) and elderly (22–26...
Articles
Clin Sci (Lond) (1999) 97 (2): 215–223.
Published: 28 June 1999
... expenditure (by indirect calorimetry) and circulating levels of catabolic (cortisol) and anabolic [testosterone, insulin-like growth factor-I (IGF-I)] hormones. Compared with the patients with a weight loss of < 10%, those with a weight loss of ⩾ 10% were characterized by higher levels of sTNF-R55 (trend...
Articles
Clin Sci (Lond) (1988) 74 (3): 255–259.
Published: 01 March 1988
... and the Medical Research Society 1970 adrenal cortex catecholamines prolactin psychological stress testosterone thyroid hormones Clinical Science (1988) 74,255-259 255 Endocrine effects of examination stress C. G. SEMPLE', C. E. GRAY2, W. B O U N D 2 , C. A. ESPIE3 AND G. H. BEASTALL2 'Department...
Articles
Clin Sci (Lond) (1983) 64 (3): 307–314.
Published: 01 March 1983
...M. Jawed Iqbal; Maureen Dalton; Robert S. Sawers 1. The percentage binding of testosterone (T) and oestradiol (E 2 ) to sex hormone binding globulin (SHBG) and human serum albumin (HSA) was determined over a range of SHBG concentrations of 16–250 nmol of dihydrotestosterone (DHT) bound/l...
Articles
Clin Sci Mol Med (1978) 55 (3): 301–307.
Published: 01 September 1978
... after ADH. 4. Castration, 24 h before study, abolished the ADH-induced fall in PRA, and testosterone implanted before castration did not restore the response. Cyproterone acetate reversed the ADH effect in males, so that PRA then rose after ADH. Hypophysectomized male rats, with depressed basal plasma...