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Keywords: therapeutic
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (4): 215–229.
Published: 31 October 2012
... summarizes the IGF system in physiology and disease before focusing on recent studies on the regulation and actions of IGFBP-6, and its potential roles in cancer cells. Given the widespread interest in IGF inhibition in cancer therapeutics, increasing our understanding of the mechanisms underlying...