... hypertension which had not responded satisfactorily to other treatment. 3. Patients were treated initially with prazosin; polythiazide, or polythiazide plus tolamolol, were added when necessary. 4. A satisfactory blood pressure response to prazosin alone, or prazosin in dual or triple combination therapy...

...-adrenoreceptor antagonists hypertension metoprolol oxprenolol practolol propranolol tolamolol Clinical Science and Molecular Medicine (1976) 51, 541tS44s. Comparative anti-hypertensive effectiveness of padrenoreceptor antagonists with different pharmacological properties: dose-response studies during...

...M. J. West; P. Sleight; A. J. Honour 1. The average blood pressure over 24 h and its variability were measured in eight unrestricted subjects before and after commencing therapy with a new β-adrenoreceptor-blocking agent, tolamolol. 2. The drug caused a fall of 15±6 mmHg in mean arterial pressure...