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Keywords: transcriptomics
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Articles
Clin Sci (Lond) (2024) 138 (5): 269–288.
Published: 27 February 2024
... day 5 to 15 in wild-type but not homozygote rat kidneys. The transcriptomic profile of renal tissue revealed several dysregulated pathways due to the lack of Xdh expression with the remodeling in inflammasome, purinergic signaling, and redox homeostasis. Further analysis suggested that lack of Xdh...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2024) 138 (4): 205–223.
Published: 21 February 2024
... the cellular mechanisms that underlie female resilience, we utilized blood–brain barrier (BBB) and hippocampal transcriptomic analyses in heterozygous mice before seizure onset (pre-TC) and in mice that experienced ∼20 TCs (post-TC). Results : In the pre-TC latent phase, both sexes exhibited leaky BBB; however...
Includes: Supplementary data
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Articles
Clin Sci (Lond) (2019) 133 (2): 239–252.
Published: 22 January 2019
... correlated with cGMP levels consistent with a NEP-dependent anti-fibrotic effect. To dissect the molecular mechanisms associated with the anti-fibrotic effects of NEP inhibition, we performed a ‘deep serial analysis of gene expression (Deep SAGE)’ transcriptome and targeted metabolomics analysis of total...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2018) 132 (20): 2269–2284.
Published: 29 October 2018
... represents acute rejection, a molecular study was performed. The transcriptome of eIV ( n =6), T cell-mediated vascular rejection with rich TI (T cell-mediated vascular rejection, TCMRV, n =4) and non-rejection histologic findings ( n =8) was compared using microarrays. A total of 310 genes were identified...
Includes: Supplementary data
Articles