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Keywords: transdifferentiation
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Clin Sci (Lond) (2010) 118 (6): 411–420.
Published: 14 December 2009
... vivo . In conclusion, our present findings demonstrate that HSC transdifferentiation is associated with increased AMPK activity that could relate to the stabilization of AMPK complex by the γ3 subunits. Activation of AMPK in HSCs inhibits in vitro fibrogenesis. By contrast, low AMPK activity does not...
Includes: Supplementary data
Clin Sci (Lond) (2005) 108 (4): 309–321.
Published: 22 March 2005
... differentiated cell types can transdifferentiate (or convert) into a completely different phenotype. Harnessing transdifferentiated cells as a therapeutic modality will complement the use of embryonic and adult stem cells in the treatment of degenerative disorders. In this review, we will examine some examples...
Clin Sci (Lond) (2002) 103 (4): 355–369.
Published: 27 August 2002
... transdifferentiation transplants 355Clinical Science (2002) 103, 355 369 (Printed in Great Britain) + R E V I E W Adult stem cell plasticity: new pathways of tissue regeneration become visible Stuart J. FORBES Pamela VIG Richard POULSOM*, Nicholas A. WRIGHT* and Malcolm R. ALISON* *Histopathology Unit, Cancer...