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Keywords: transforming growth factors
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Clin Sci (Lond) (2023) 137 (20): 1593.
Published: 20 October 2023
... renal fibrosis transforming growth factors The authors of the original article, “MKP2 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in renal tubular epithelial cells through a JNK-dependent pathway” (doi: 10.1042/CS20180602 ), would like to correct their paper. The authors have...
Clin Sci (Lond) (2022) 136 (16): 1229–1240.
Published: 31 August 2022
... in mitigating age-associated fibrosis. While transforming growth factor-β1 (TGF-β1) is a central mediator of fibrosis in almost all contexts, and across multiple organs, it is not feasible to target this canonical pathway at the ligand–receptor level due to the pleiotropic nature of its actions; importantly...
Clin Sci (Lond) (2019) 133 (3): 545–550.
Published: 13 February 2019
... and is prominently induced by the transforming growth factor-β 1 (TGF-β1). TGF-β1 signals through a variety of Smad and non-Smad signaling pathways, including the mitogen-activated protein kinase (MAPK) pathways. In a study published in a recent issue of Clinical Science (Clin. Sci. (2018) 132(21),2339–2355), Li et...
Clin Sci (Lond) (2018) 132 (21): 2339–2355.
Published: 13 November 2018
...-specificity MKPs that regulate the MAP kinase pathway involved in transforming growth factor-β1 (TGF-β1)-induced EMT. However, the function of MKP2 in the regulation of EMT and the underlying mechanisms are still largely unknown. In the present study, we detected the expression of MKP2 in an animal model...
Includes: Supplementary data