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Keywords: translational research
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Clin Sci (Lond) (2017) 131 (14): 1617–1629.
Published: 30 June 2017
... of translation. CKD was among the fastest growing causes of death in the past 20 years in age-adjusted terms. The gap between recent advances and the growing worldwide mortality appears to result from sequential roadblocks that limit the flow from basic research to clinical development (translational research...
Clin Sci (Lond) (2012) 122 (10): 439–447.
Published: 20 January 2012
... microRNA markers detectable in body fluids. We discuss the lessons learned and the experience gained from these studies. Several recent studies have begun to explore translational microRNA research in kidney disease and hypertension. Translational research of microRNAs in the kidney faces unique challenges...
Clin Sci (Lond) (2010) 119 (10): 423–429.
Published: 05 August 2010
... Society 2010 cardiovascular disease diabetes mellitus hyperlipidaemia inflammation innate immune system periodontitis translational research The innate immune system contributes to the development of T2DM [Type 2 DM (diabetes mellitus)] [ 1 , 2 ]. In this model, it was suggested...
Clin Sci (Lond) (2007) 112 (4): 217–227.
Published: 17 January 2007
... and increase confidence in drug candidates, understand the therapeutic index in humans, enhance cost-effective decision making in exploratory development and increase phase II success. Translational research is one of the most important activities of translational medicine as it supports predictions about...
Clin Sci (Lond) (2005) 109 (5): 421–430.
Published: 24 October 2005
... biomarker genomics protein expression proteomics renal disease translational research In a blueprint for the genomic era, the US NHGRI (National Human Genome Research Institute) laid out the major challenges ahead in harnessing the potential of the Human Genome Project to improve humanity's...