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Keywords: translational research
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Clin Sci (Lond) (2017) 131 (14): 1617–1629.
Published: 30 June 2017
... translation. CKD was among the fastest growing causes of death in the past 20 years in age-adjusted terms. The gap between recent advances and the growing worldwide mortality appears to result from sequential roadblocks that limit the flow from basic research to clinical development (translational research...
Clin Sci (Lond) (2012) 122 (10): 439–447.
Published: 20 January 2012
... microRNA markers detectable in body fluids. We discuss the lessons learned and the experience gained from these studies. Several recent studies have begun to explore translational microRNA research in kidney disease and hypertension. Translational research of microRNAs in the kidney faces unique challenges...
Clin Sci (Lond) (2010) 119 (10): 423–429.
Published: 05 August 2010
... fulfils many of the Bradford Hill criteria [ 23 ] ( Table 2 ) and we also suggest future translational research studies to try and test our hypothesis further ( Table 3 ). Table 2 Is periodontitis a causative factor in T2DM? A consideration of Bradford Hill's criteria [ 23 ] Criterion...
Clin Sci (Lond) (2009) 116 (4): 283–299.
Published: 15 January 2009
... Society 2009 atherosclerosis endothelial function endothelial progenitor cell smooth muscle progenitor cell translational research The last decade has seen a huge interest in the field of regenerative biology, with particular emphasis on the use of isolated or purified stem and...
Clin Sci (Lond) (2007) 112 (4): 217–227.
Published: 17 January 2007
... increase confidence in drug candidates, understand the therapeutic index in humans, enhance cost-effective decision making in exploratory development and increase phase II success. Translational research is one of the most important activities of translational medicine as it supports predictions about...
Clin Sci (Lond) (2005) 109 (5): 421–430.
Published: 24 October 2005
... proteomics renal disease translational research In a blueprint for the genomic era, the US NHGRI (National Human Genome Research Institute) laid out the major challenges ahead in harnessing the potential of the Human Genome Project to improve humanity's health and well being [ 1 ]. In their...