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Keywords: transthyretin
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Clin Sci (Lond) (2023) 137 (5): 355–366.
Published: 09 March 2023
...João Moreira; Helena Martins; Margarida Saraiva; Maria João Saraiva Hereditary amyloid transthyretin (ATTRv) amyloidosis is a fatal neurodegenerative disorder, first identified in Portugal. The most common transthyretin (TTR) mutation in ATTRv results from an exchange of a methionine for a valine...
Includes: Supplementary data
Clin Sci (Lond) (2016) 130 (18): 1665–1675.
Published: 08 August 2016
...Cristina A. Teixeira; Maria do Rosário Almeida; Maria João Saraiva Transthyretin (TTR)-related amyloidoses are diseases characterized by extracellular deposition of amyloid fibrils and aggregates in tissues composed of insoluble misfolded TTR that becomes toxic. Previous studies have demonstrated...