...: a single prolonged bout of aerobic exercise [2 h at 60% of V ̇ O 2 peak (peak oxygen consumption)] reduces fasting plasma TAG [triacylglycerol (triglyceride)] concentrations, via enhanced clearance of VLDL-TAG from the circulation, whereas the same exercise performed for 1 h has no effect on VLDL-TAG...

...Yiannis E. Tsekouras; Faidon Magkos; Konstantinos I. Prentzas; Konstantinos N. Basioukas; Stergoula G. Matsama; Amalia E. Yanni; Stavros A. Kavouras; Labros S. Sidossis A single bout of prolonged aerobic exercise lowers plasma TAG (triacylglycerol) concentrations the next day by increasing...

... understood. This short review highlights the effect of increasing fat mass on ectopic fat accumulation, the role of triacylglycerols (triglycerides) in Type 2 diabetes mellitus and cardiovascular disease pathogenesis, and selected current therapeutic strategies used to ameliorate these risk factors...

... 2008 apolipoprotein B (apoB) dyslipidaemia lipoprotein low-density lipoprotein (LDL) non-high-density lipoprotein cholesterol (non-HDL-C) triacylglycerol very-low-density lipoprotein (VLDL) Non-HDL-C [non-HDL (high-density lipoprotein) cholesterol] was introduced by ATP III (Adult...

... activation. The mechanisms of fatty acids to induce cell death involved changes in mitochondrial transmembrane potential and intracellular neutral lipid accumulation. Fatty acids poorly incorporated into triacylglycerol had the highest toxicity. apoptosis fatty acid J774 cell macrophage necrosis...

...Wenjie YANG; Jianfeng HUANG; Cailiang YAO; Shaoyong SU; Donghai LIU; Dongliang GE; Dongfeng GU Elevated TG [triacylglycerol (triglyceride)] is a significant independent risk factor for cardiovascular disease. LPL (lipoprotein lipase) is one of the key enzymes in the metabolism of the TG-rich...

... that the Trp64Arg amino acid variant of the β 3 AR is associated with hypertension and higher serum triacylglycerol levels in the Sardinian population. The aim of the present study was to evaluate the effect of the Trp64Arg β 3 AR variant on the regulation of triacylglycerol levels and blood pressure during...

...Jason M.R. GILL; Sara L. HERD; Natassa V. TSETSONIS; Adrianne E. HARDMAN Moderate exercise improves insulin sensitivity and reduces triacylglycerol (triglyceride; TG) concentrations. We hypothesized that changes in insulin sensitivity are an important determinant of exercise-induced changes...

...Jason M. R. GILL; Keith N. FRAYN; Stephen A. WOOTTON; George J. MILLER; Adrianne E. HARDMAN Moderate exercise reduces postprandial triacylglycerol concentrations, which are a risk marker for coronary heart disease. The present study sought to determine the qualitative nature of exercise-induced...

... were selected through local general practices on the basis of a moderately raised plasma triacylglycerol (triglyceride) level (> 1.5 mmol/l) and a low concentration of high-density-lipoprotein cholesterol (< 1.1 mmol/l). The screening of LDL subclasses revealed a predominance of small, dense LDL...

... of the phospholipid membrane bilayer. 4. Basal calcium pump activity was lower in the hyperlipidaemic group with increased membrane fluidity. 5. These results suggest that membrane adaptive mechanisms can maintain membrane cholesterol within a narrow range, that serum triacylglycerol is more important than serum...

... concentrations of plasma triacylglycerol (1510 ± 150 versus 850 ± 80 μmol/l, P < 0.01), blood ketone bodies (151 ± 21 versus 80 ± 10 μmol/l, P < 0.01) and plasma insulin (17 ± 3 versus 7 ± 1 m-units/l, P < 0.01) were elevated compared with the postabsorptive state; plasma glucose and non-esterified...

... be used to define the role of excessive lipolysis in experimental (and human) pathophysiology. 14 1 1993 26 1 1993 © 1993 The Biochemical Society and the Medical Research Society 1993 adenosine A 1 -receptors diabetes GR79236 non-esterified fatty acids triacylglycerol...

...Mahmoud M. Farag; Amel T. Hassib 1. The relationship between serum triacylglycerol concentration and hepatic microsomal enzyme activity was examined in rats. 2. Two groups of rats were injected with diclofenac sodium at doses of 2.5 and 5 mg day −1 kg −1 . A third group was injected...

... to triacylglycerol. 5 5 1992 17 7 1992 © 1992 The Biochemical Society and the Medical Research Society 1992 cirrhosis C-peptide C-peptide metabolic clearance rate glucose glycerol 3-hydroxybutyrate insulin secretion lactate non-esterified fatty acids triacylglycerol Clinical...

... that certain oral contraceptive compounds can alter erythrocyte cation transport, and indicate that norethisterone in higher dose preparations is the component predominantly responsible. The alterations observed could not be explained by a direct link with concurrent changes in plasma triacylglycerol...

...Keith N. Frayn; Simon W. Coppack © 1992 The Biochemical Society and the Medical Research Society 1992 adipose tissue coronary heart disease insulin insulin resistance lipoproteins non-esterified fatty acids triacylglycerol Clinical Science (1992) 82, 1-8 (Printed in Great Britain...

...Jennifer L. Potts; Rachel M. Fisher; Sandy M. Humphreys; Simon W. Coppack; Geoffrey F. Gibbons; Keith N. Frayn 1. Triacylglycerol extraction by subcutaneous adipose tissue and forearm muscle was studied in nine normal subjects after an overnight fast and after the consumption of a mixed meal. 2...

...Brice Lerique; Marguerite Gastaldi; Jean Boyer 1. Triacylglycerol in erythrocytes from normal human subjects was estimated to average 2.7 ± 0.7 nmol/10 10 cells, equivalent to 0.07% of total lipids or 0.3% of neutral lipids. 2. The specific activity of triacylglycerol labelling attained...

...P. J. Grant; E. K. O. Kruithof; C. P. Felley; J. P. Felber; F. Bachmann 1. To investigate the acute effects of insulin and triacylglycerol (‘triglyceride’) on circulating plasminogen activator inhibitor-1 concentrations, seven healthy volunteers were studied during hyperinsulinaemic clamps...

..., mainly in the form of non-esterified fatty acids. 3. After the meal, arterialized plasma concentrations of glucose and lactate rose sharply (peak at 60 min), whereas those of non-esterified fatty acids and glycerol fell (nadir at 60–120 min). Plasma triacylglycerol concentrations rose slowly to peak...

... the adipose tissue showed marked positive carbon balance (net substrate deposition). 7 6 1989 23 6 1989 © 1989 The Biochemical Society and the Medical Research Society 1989 adipose tissue free fatty acids glucose glycerol insulin lactate muscle triacylglycerol Clinical Science...

... to control rats, although the liver triacylglycerol content was significantly increased. From the second week of feeding, fatty acid synthesis rates were significantly lower in alcohol-fed rats and the liver triacylglycerol content progressively increased compared with controls. 3. Fatty acid synthase...