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Keywords: tricarboxylic acid cycle
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Articles
Ammonium Chloride Inhibits Pyruvate Oxidation in Rat Liver Mitochondria: A Possible Cause of Fatty Liver in Reye's Syndrome and Urea Cycle Defects
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1994) 87 (5): 499–503.
Published: 01 November 1994
... a slight activating effect in the absence or presence of NH 4 Cl. 4. These results indicate that NH 4 Cl inhibits the oxidative metabolism of acetyl-CoA in the tricarboxylic acid cycle. Therefore, inhibition of fatty acid oxidation to acetyl-CoA as well as its further oxidative metabolism occurring under...