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Keywords: type 1 diabetes
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Clin Sci (Lond) (2021) 135 (1): 19–34.
Published: 05 January 2021
...; Niels Olsen Saraiva Camara; Alessandra Pontillo; Rui Curi Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by insulin-producing pancreatic β-cell destruction and hyperglycemia. While monocytes and NOD-like receptor family-pyrin domain containing 3 (NLRP3) are associated...
Includes: Supplementary data
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Clin Sci (Lond) (2017) 131 (23): 2835–2845.
Published: 28 November 2017
.... Furthermore, we demonstrate that these beneficial effects on islet function can be partly attributed to the MSC-derived products ECM and ANXA1. Conclusions: Our results suggest that hASCs have the potential to improve the quality of human islets isolated for transplantation therapy of Type 1 diabetes...
Includes: Supplementary data
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Clin Sci (Lond) (2016) 130 (1): 45–56.
Published: 30 November 2015
... Type 1 diabetes Type 2 diabetes • Impairment of skin wound repair is a major complication of diabetes, favouring development of foot ulcers and contributing to their poor prognosis. Improving skin healing is a therapeutic issue in diabetic patients. • Our study revealed that treatment...
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Clin Sci (Lond) (2010) 118 (2): 87–97.
Published: 12 October 2009
...Michael D. McCall; Christian Toso; Emmanuel E. Baetge; A. M. James Shapiro With the already heightened demand placed on organ donation, stem cell therapy has become a tantalizing idea to provide glucose-responsive insulin-producing cells to Type 1 diabetic patients as an alternative to islet...
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Clin Sci (Lond) (2009) 116 (7): 565–574.
Published: 02 March 2009
... transcription and altered cell phenotype. In diabetic animals and Type 1 diabetic patients, short-term studies indicate that C-peptide also enhances glucose disposal and metabolic control. Furthermore, results derived from animal models and clinical studies in Type 1 diabetic patients suggest a salutary effect...
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Clin Sci (Lond) (1998) 94 (3): 255–261.
Published: 01 March 1998
... in Type 1 diabetes patients with neuropathy. 4. The ratio between capillary blood flow and total skin perfusion decreased significantly in the control group (from 0.82 ± 0.15 to 0.47 ± 0.11; P < 0.005) and in the Type I diabetes patients without neuropathy (from 0.79 ± 0.12 to 0.43 ± 0.12; P < 0.05...
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Clin Sci (Lond) (1987) 72 (1): 123–130.
Published: 01 January 1987
...J. Kastrup; T. Nørgaard; H.-H. Parving; N. A. Lassen 1. The distensibility of the resistance vessels of the skin at the dorsum of the foot was determined in 11 long-term type 1 (insulin-dependent) diabetic patients with nephropathy and retinopathy, nine short-term type 1 diabetic patients without...