... 2012 11 2 2013 13 2 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 angiotensin-(1–7) hypertension Mas receptor noradrenaline (norepinephrine) synapse tyrosine hydroxylase The RAS (renin–angiotensin system) is one of the major systems...

...Laiyuan Wang; Biao Li; Xiangfeng Lu; Qi Zhao; Yun Li; Dongliang Ge; Hongfan Li; Penghua Zhang; Shufeng Chen; Runsheng Chen; Boqin Qiang; Dongfeng Gu The TH (tyrosine hydroxylase) gene encodes the rate-limiting enzyme of catecholamine biosynthesis, and is involved in the pathogenesis of hypertension...

... -methyltransferase tyrosine hydroxylase Clinical Science (1981) 61,227~230s 221s Differences in utero in activities of catecholamine biosynthetic enzymes in adrenals of spontaneously hypertensive rats G. T E I T E L M A N , R . A . R O S S , T. H. J O H A N D D . J . R E I S Laboratory of Neurobiology...

... after 3 weeks. 3. Hypothalamic tyrosine hydroxylase and dopamine β-hydroxylase activities, and the concentration of noradrenaline were increased in the Goldblatt I animals after 3 weeks. 4. Enhanced hypothalamic noradrenaline synthesis may be a pathogenic factor in Goldblatt I renovascular hypertension...

...Margaret A. Petty; John L. Reid 1. Noradrenaline content of several rat brain stem and hypothalamic nuclei falls transiently at 72 h after initiation of renovascular hypertension (one-kidney Goldblatt model). 2. Tyrosine hydroxylase activity is significantly reduced in posterior, paraventricular...

...B. Jarrott; W. J. Louis 1. The activities of the enzymes involved in catecholamine synthesis, tyrosine hydroxylase, aromatic amino acid decarboxylase and dopamine β-hydroxylase, were markedly enhanced in homogenates of phaeochromocytoma compared with human adrenal medulla homogenates measured under...

.... In the adrenal glands of adult DOCA—salt hypertensive rats tyrosine hydroxylase activity was increased. 6. These results implicate peripheral noradrenaline-containing neurons and central adrenaline-containing neurons in the development of genetic and experimental hypertension in rats. © 1976 The Biochemical...

...T. Kimura; E. Takahashi; M. Ozawa; S. Uchiyama; S. Maekawa; O. Yashima; M. Sato 1. A clinical study of pyratrione, a tyrosine hydroxylase inhibitor, has been carried out in essential hypertension. 2. Out of thirty-nine patients who received pyratrione, twenty-eight showed a significant decrease...