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Keywords: unfolded protein response
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Clin Sci (Lond) (2021) 135 (23): 2643–2658.
Published: 08 December 2021
... (RTECs) and systemically accumulates in CKD patients [ 7 ]. Recently, it has caught more attention for its systemically detrimental effects in CKD patients [ 6 , 8 , 9 ] but not in the AKI population. It is well documented that the unfolded protein responses (UPRs) signaling is activated...
Includes: Supplementary data
Clin Sci (Lond) (2010) 118 (1): 19–29.
Published: 28 September 2009
...Toru Hosoi; Koichiro Ozawa Various stresses, which impair ER (endoplasmic reticulum) function, lead to an accumulation of unfolded or misfolded proteins. ER stress triggers many rescuer responses, including a UPR (unfolded protein response). Increasing evidence has suggested that ER stress...