[email protected] ). 28 11 2001 8 4 2001 The Biochemical Society and the Medical Research Society © 2002 2002 arginase arginine endothelium nitric oxide urea cycle uraemia 31Clinical Science (2002) 103, 31 41 (Printed in Great Britain) Altered L-arginine metabolism results...

... with argininosuccinic aciduria resulted in a much higher degree of labelling of the plasma globulins than the albumin. This is consistent with a considerable turnover of hepatic arginine, as would be expected with a functioning Krebs-Henseleit urea cycle. 4. These results can be explained with a compartmentation model...