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Clin Sci (Lond) (2002) 103 (5): 475–485.
Published: 11 October 2002
... through direct perturbation of mitochondrial membrane structure and function. In contrast, ursodeoxycholate (UDC) and its taurine-conjugated form (TUDC) appear to be protective. We show here that hydrophobic bile salts induced apoptosis in cultured rat hepatocytes, without modulating the expression of pro...
Clin Sci (Lond) (1988) 75 (6): 593–599.
Published: 01 December 1988
... transport into bile. By contrast, ursodeoxycholate induces hypercholeresis, partly due to a marked stimulation of biliary bicarbonate secretion. The aim of the present work was to investigate the effect of protoporphyrin IX on ursodeoxycholate-induced choleresis in anaesthetized male Wistar rats. 2...
Clin Sci (Lond) (1984) 66 (4): 487–491.
Published: 01 April 1984
...S. Erlinger; M. Dumont; I. Zouboulis-Vafiadis; G. De Couet 1. The biliary maximum secretory rate (SR max. ) of glycoursodeoxycholate in the bile fistula anaesthetized rat was about five times that of unconjugated ursodeoxycholate. 2. Likewise, the biliary SR max. of tauro-7-ketolithocholate was...