... Vascular Biology RAECs and VSMCs were stimulated with OPG (50 ng/ml) for 5, 15, 30 and/or 60 min. In some experiments, VSMCs were pre-incubated with SSNT (10 µmol/l), NoxA1ds (10 µmol/l), a dual Nox1/Nox4 inhibitor, GKT137831 (10 µmol/l), heparinase I (1 mU/ml) or chondroitinase (1 mU/ml) for 30 min...

... The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 cardiovascular disease extracellular matrix flow-induced shear stress mechanical stimuli mechanotransduction vascular biology Deciphering the role of hemodynamic forces in homeostasis...

... as distinct. In this editorial, we provide an overview of mechanisms related to differences in vascular pathophysiology between men and women and explore the contributions of both sex and gender. Gender Ischaemic heart disease Sex Vascular biology Cardiovascular disease (CVD) is a leading cause...