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Keywords: vascular dysfunction
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Clin Sci (Lond) (2019) 133 (7): 885–904.
Published: 12 April 2019
... vessel tone are altered by oxidative damage of vascular endothelial cells, thus promoting vascular dysfunction, a key driver of CVD. In this review, the detrimental role of oxidative stress in COPD and comorbid CVD are discussed and we propose that targeting oxidant-dependent mechanisms represents...
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Clin Sci (Lond) (2015) 129 (2): 159–167.
Published: 24 April 2015
... reverse vascular dysfunction in aged human skin through NO-dependent mechanisms [ 4 , 13 ]. However, the high cost and relative unavailability of oral formulations of BH 4 underscore the need for a readily available, inexpensive, intervention strategy to effectively improve microvascular function...
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Clin Sci (Lond) (2013) 124 (5): 333–342.
Published: 16 November 2012
...Kathleen M. Lukaszewicz; John R. Falck; Vijaya L. Manthati; Julian H. Lombard The present study tested the hypothesis that the Dahl SS (salt-sensitive) rat has vascular dysfunction due, in part, to the up-regulation of the CYP4A/20-HETE (cytochrome P450 ω-hydroxylase 4A)/20-hydroxyeicosatetraenoic...
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Clin Sci (Lond) (2008) 115 (9): 295–300.
Published: 01 October 2008
...Faisel Khan; Dean Patterson; Jill J.F. Belch; Kumiko Hirata; Chim C. Lang Vascular dysfunction in the coronary and peripheral circulations is an early prognostic marker of future cardiovascular events. Measurements of coronary and peripheral vascular function in resistance vessels can be made...
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