...Ernesto L. Schiffrin There have been few new treatments introduced for hypertension in the last thirty years. The endothelin (ET) system was discovered in 1988, and in the following years, it was demonstrated that it participated in the elevation of blood pressure and vascular remodeling...

... the initial triggering event. Clinical data indicate that despite treatment with antihelminthics such as praziquantel, schistosomiasis PH in humans persists and progresses [ 5–7 ]. Furthermore, modern autopsy case series of individuals who died of Schistosoma -PH reveal substantial vascular remodeling...

... to identify the mechanisms underlying vascular complications during pre-eclampsia with the aim of identifying targetted interventions for prevention and treatment of cardiovascular diseases. Although many factors influence the initiation and rate of vascular remodeling in humans, there are a few...

.... angiotensin high-fat diet vascular remodeling abdominal aortic aneurysm MMP Correspondence: Elena Kaschina ( [email protected] ) * These authors contributed equally to this work. 10 02 2017 21 06 2017 23 06 2017 23 06 2017 © 2017 The Author(s...