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Keywords: vasopressin
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (23): 2619–2623.
Published: 08 December 2021
...Natalia M. Noto; Yazmin M. Restrepo; Robert C. Speth It is well-established that Ang-(1-7) counteracts the effects of Ang II in the periphery, while stimulating vasopressin release and mimicking the activity of Ang II in the brain, through interactions with various receptors. The rapid metabolic...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (17): 2121–2126.
Published: 10 September 2021
... pathophysiology. colitis dendritic cells neurohypophysis neurosecretion oxytocin vasopressin Correspondence: Morley D. Hollenberg ( [email protected] ) 30 04 2021 16 08 2021 20 08 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (14): 1727–1731.
Published: 22 July 2021
...) (2021) 135 :1353–1367) generated a transgenic mouse model overexpressing full-length rat angiotensinogen in astrocytes, and observed massively elevated brain Ang II levels, increased sympathetic nervous activity and vasopressin, and up-regulated erythropoiesis. Yet, blood pressure and kidney function...
Articles
Sabrina M. Scroggins, Donna A. Santillan, Jenna M. Lund, Jeremy A. Sandgren, Lindsay K. Krotz, Wendy S. Hamilton, Eric J. Devor, Heather A. Davis, Gary L. Pierce, Katherine N. Gibson-Corley, Curt D. Sigmund, Justin L. Grobe, Mark K. Santillan
Journal:
Clinical Science
Clin Sci (Lond) (2018) 132 (3): 419–436.
Published: 14 February 2018
... disorder of pregnancy, involves imbalanced T helper (T H ) cell populations and resultant changes in pro- and anti-inflammatory cytokine release. Elevated copeptin (an inert biomarker of arginine vasopressin (AVP)), secretion precedes the development of symptoms in PreE in humans, and infusion of AVP...
Includes: Supplementary data
Articles
Jing-Yi Lee, Teh-Ia Huo, Hui-Chun Huang, Fa-Yauh Lee, Han-Chieh Lin, Chiao-Lin Chuang, Ching-Chih Chang, Sun-Sang Wang, Shou-Dong Lee
Journal:
Clinical Science
Clin Sci (Lond) (2011) 121 (12): 545–554.
Published: 22 August 2011
... is unknown. Portal hypertension was induced by PVL (portal vein ligation) in Sprague–Dawley rats. In an acute study with an in situ perfusion model, the collateral responsiveness to AVP (arginine vasopressin) was evaluated with vehicle, propranolol (10 μmol/l), propranolol plus suramin (100 μmol/l, a G α...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2003) 105 (1): 1–8.
Published: 01 July 2003
... cirrhosis vasopressin Clinical Science (2003) 105, 1 8 (Printed in Great Britain) 1 R E V I E W Therapeutic role of vasopressin receptor antagonism in patients with liver cirrhosis James Walter FERGUSON , George THERAPONDOS , David E NEWBY and Peter Clive HAYES Department of Medicine, Royal Infirmary...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2002) 103 (s2002): 162S–166S.
Published: 01 September 2002
...Noreen F. ROSSI; Haiping CHEN The endothelins (ETs) stimulate the secretion of arginine-vasopressin (AVP) in vivo and in vitro . The activation of hypothalamic ET B receptors increases AVP release, but the neurotransmitters mediating these responses are not known. In the compartmentalized...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1998) 94 (5): 517–523.
Published: 01 May 1998
...J. Risvanis; C. I. Johnston; P. A. Phillips; L. M. Burrell 1. Vasopressin V1a and V2 receptors are differentially regulated in deoxycorticosterone acetate-salt hypertension. This paper investigated whether the changes were due to transcription changes in receptor mRNA assessed by in situ...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (5): 601–606.
Published: 01 November 1996
... to study contraction after pressure recording. 3. Octreotide treatment significantly reduced portal pressure and plasma glucagon concentrations compared with the vehicle-treated group. Both phenylephrine and vasopressin induced concentration-dependent contractile responses in the aorta and mesenteric...
Articles
Paddy A. Phillips, John Risvanis, Anne-Marie Hutchins, Louise M. Burrell, Duncan MacGregor, Andrew L Gundlach, Colin I. Johnston
Journal:
Clinical Science
Clin Sci (Lond) (1995) 88 (6): 671–674.
Published: 01 June 1995
...Paddy A. Phillips; John Risvanis; Anne-Marie Hutchins; Louise M. Burrell; Duncan MacGregor; Andrew L Gundlach; Colin I. Johnston 1. To investigate the mechanism of hepatic V1a vasopressin receptor down-regulation in streptozotocin-induced diabetes mellitus in the rat, we measured hepatic V1a...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1995) 88 (2): 165–172.
Published: 01 February 1995
.... Haemodynamic variables, and plasma concentrations of atrial natriuretic peptide, arginine vasopressin, adrenaline and noradrenaline were measured. 3. Right atrioventricular pacing at a rate of 150 impulses/min resulted in disparate responses in right atrial pressure (slight decrease) and pulmonary capillary...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1994) 87 (4): 389–395.
Published: 01 October 1994
...Louise M. Burrell; Paddy A. Phillips; K. A. Rolls; B. F. Buxton; C. I. Johnston; J. J. Liu 1. The effects of the non-peptide arginine vasopressin V 1 receptor antagonist (OPC-21268) and the non-peptide V 2 receptor antagonist (OPC-31260) on vasopressin-induced contraction of human internal mammary...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1993) 85 (4): 487–494.
Published: 01 October 1993
... with a dose-dependent increase in proximal tubular sodium reabsorption as assessed by the lithium clearance method. Fractional reabsorption of sodium by the distal nephron was, however, unchanged by noradrenaline in both hydration states. 5. Plasma vasopressin concentration was unchanged by noradrenaline...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 83 (5): 583–587.
Published: 01 November 1992
...Nicholas B. Argent; Robert Wilkinson; Peter H. Baylis 1. The metabolic clearance rate of arginine vasopressin was determined using a constant infusion technique in normal subjects and patients with chronic renal failure immediately before commencing dialysis. Endogenous arginine vasopressin...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 83 (4): 467–475.
Published: 01 October 1992
...P. Eiken; C. Emmeluth; H. J. Schütten; P. Bie 1. The renal effects of angiotensin II were investigated (a) with and without acute blockade of the effects of aldosterone and (b) with and without concomitant infusion of vasopressin. Angiotensin II (2 ng min −1 kg −1 ) and/or vasopressin (5 pg min −1...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1991) 81 (2): 257–260.
Published: 01 August 1991
...K. K. Hampton; P. J. Grant; J. Primrose; H. G. Dean; J. A. Davies; C. R. M. Prentice 1. During major abdominal surgery there are increases in Factor VIII and plasminogen activator activity, associated with elevated plasma concentrations of vasopressin, of a magnitude shown to affect haemostasis. 2...
Articles
D. J. S. Carmichael, M. S. Sutters, R. J. Unwin, D. Gordon, J. Few, V. H. T. James, J. Wadsworth, W. S. Peart
Journal:
Clinical Science
Clin Sci (Lond) (1990) 78 (6): 605–612.
Published: 01 June 1990
.... Urine flow rate tended to increase on the first day of sodium restriction and this reached statistical significance in the group initially on a high sodium intake (64.0 ± 8.8 to 84.3 ± 11.2 ml/h, P <0.01); although the pattern of urine flow did correlate with plasma arginine vasopressin concentration...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1989) 77 (5): 467–471.
Published: 01 November 1989
...Alan J. Knox; John R. Britton; Anne E. Tattersfield 1. Recent evidence suggests that a high salt diet increases bronchial reactivity, but the underlying mechanism is unclear. 2. To determine whether alterations in circulating vasopressin might be responsible, we have studied the effect...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1989) 76 (6): 667–671.
Published: 01 June 1989
...L. F. O. Obika; J. F. Laycock 1. The cardiovascular effects of pressor doses of arginine vasopressin were examined in anaesthetized Brattleboro rats with hereditary diabetes insipidus (BDI) and normal rats of the parent Long Evans (LE) strain, either 37 or 85 days old. 2. Control mean arterial...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 75 (5): 449–453.
Published: 01 November 1988
...S. J. Bund; A. M. Heagerty; C. Aalkjaer; J. D. Swales 1. The sensitivity of mesenteric resistance arterioles to [arginine]vasopressin (AVP) was investigated in spontaneously hypertensive rats (SHR) and control Wistar–Kyoto rats (WKY). No difference in pAVP (–log dose of AVP producing 50...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 75 (4): 441–444.
Published: 01 October 1988
.... Daily urine volumes were high (4454 ± 624 ml) in the quadriplegic patients secondary to habitually increased fluid intake. 3. All quadriplegic patients had suppressed plasma arginine vasopressin levels (< 0.8 pmol/l) and were able to form dilute urine after a water load (20 ml/kg). However, free...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 74 (3): 293–299.
Published: 01 March 1988
...Jean-Francois Liard 1. The specific antidiuretic agonist [4-valine, 8- d -arginine]vasopressin (VDAVP) was administered intravenously to seven conscious dogs at a rate of 10 ng min −1 kg −1 . Cardiac output (aortic electromagnetic flowmeter), mean arterial pressure and regional blood flows...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 74 (1): 49–52.
Published: 01 January 1988
... + excretion, while normal Na + (0.15 mol/1) CSF had no effects. Plasma ANP levels were higher in the high Na + CSF group than in the normal Na + group (154 ±39 vs 52 ±19 pmol/l, P < 0.05). 3. Interruption of the sympathetic nervous system and the vascular action of vasopressin with intravenous...
Articles
H. C. R. Simpson, J. E. Zubillaga, J. G. Collier, E. D. Bennett, N. Mehta, V. T. Y. Ang, J. S. Jenkins
Journal:
Clinical Science
Clin Sci (Lond) (1987) 73 (6): 589–592.
Published: 01 December 1987
... blood flow, despite an increase in plasma arginine vasopressin (AVP) during hypertonic saline. 2. Immediately and 10 min after passive tilting to 50°, mean forearm blood flow fell by 17.1 and 14.3% compared with the values in the supine position during isotonic saline and by 40.3 and 43.3% during...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 73 (4): 377–381.
Published: 01 October 1987
... of 0.9% (w/v) NaCl, were used as controls. The cisplatin-treated rats developed a pronounced polyuria which did not recover during an 18 week observation period. 2. After 21 weeks, one group of the cisplatin-treated animals received a 6 h infusion of 2.5% d -glucose. Vasopressin (60 μ-units min −1 100 g...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 73 (3): 253–258.
Published: 01 September 1987
...Yutaka Takata; Yoshiaki Yamashita; Shuichi Takishita; Masatoshi Fujishima 1. The role of the sympathetic nervous system and the effect of vasopressin (AVP) on the hypotensive action of nifedipine (Nf) were evaluated in conscious, unrestrained normotensive and DOCA–salt hypertensive rats. 2...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (5): 525–530.
Published: 01 May 1987
...K. Ogawa; L. F. Arnolda; E. A. Woodcock; M. Hiwatari; C. I. Johnston 1. This study was designed to investigate the effects of intracerebroventricular or intravenous atrial natriuretic peptide (ANP) on plasma arginine-vasopressin (AVP) levels, plasma renin activity (PRA), blood pressure (BP...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (1): 19–24.
Published: 01 January 1987
...% below baseline. 4. Changes in plasma renin, angiotensin II, aldosterone and vasopressin during the study were slight compared with the change in IR-ANP, but noradrenaline levels rose threefold during ultrafiltration. 5. There was a significant positive relationship between arterial pressure and IR-ANP...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (1): 25–30.
Published: 01 January 1987
...Giuseppe A. Sagnella; Nirmala D. Markandu; Angela C. Shore; Mary L. Forsling; Graham A. MacGregor 1. Plasma levels of immunoreactive atrial natriuretic peptide (IrANP), plasma renin activity, aldosterone and vasopressin were measured in 11 normotensive subjects on a low (10 mmol/day), a normal (150...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (6): 651–656.
Published: 01 December 1986
... marked at intervals during the infusion periods. 3. Infusion of hypertonic saline caused a steady rise in plasma osmolality together with a progressive linear increase in thirst perception and also plasma arginine vasopressin. No significant changes in thirst, plasma osmolality or plasma arginine...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (6): 633–638.
Published: 01 December 1986
...P. G. Wiles; P. J. Grant; J. A. Davies 1. Physiological elevation of plasma vasopressin in man results in a small reduction in skeletal muscle blood flow but the action on skin blood flow has not been reported. 2. We have studied eight male subjects during infusion of arginine vasopressin (AVP...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (5): 621–624.
Published: 01 November 1986
...), vasopressin (aVP) and adrenaline. 3. During nausea plasma aVP concentrations rose from median values of 0.4 pg/ml (at time 0) to 76 pg/ml at peak nausea and fell to 32 pg/ml 20 min later. Adrenaline rose from 0.36 to 0.91 nmol/l ( P < 0.05) before falling to 0.55 nmol/l. 4. During nausea, FVIIIC rose from...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (4): 357–365.
Published: 01 October 1986
...% NaCl for 2 days before the experiment. 2. Inhibition of the renin-angiotensin (ANG) system (with captopril) and of the cardiovascular actions of vasopressin [with 1-(β-mercapto-β,β-cyclopentamethylenepropionic acid), 8- d -arginine vasopressin (d(CH 2 ) 5 DAVP)] had no hypotensive effects in sham...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (2): 167–171.
Published: 01 August 1986
...G. I. Russell; N. P. Godfrey; M. L. Forsling; R. F. Bing; H. Thurston; J. D. Swales 1. The induction of selective renal medullary damage by 2-bromoethylamine hydrobromide (BEA) results in polyuria and raised blood pressure. In view of the likely elevation of plasma vasopressin we have investigated...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (1): 97–104.
Published: 01 July 1986
... concentrations of arginine vasopressin (AVP), angiotensin II (ANG II) and aldosterone (Aldo), were determined before and three times during the first 4 h after loading. 2. D and C water increased to a significantly lower level ( P < 0.01) after water loading in patients with nephrotic syndrome than in control...
Articles
H. C. R. Simpson, J. E. Zubillaga, J. G. Collier, E. D. Bennett, V. T. Y. Ang, N. Mehta, J. S. Jenkins
Journal:
Clinical Science
Clin Sci (Lond) (1986) 70 (2): 177–184.
Published: 01 February 1986
...H. C. R. Simpson; J. E. Zubillaga; J. G. Collier; E. D. Bennett; V. T. Y. Ang; N. Mehta; J. S. Jenkins 1. Ten healthy volunteers received intravenous infusions of arginine vasopressin (AVP) at 0.1 m-unit min −1 kg −1 and 5% d -glucose on separate days. AVP caused a small fall in forearm blood flow...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1985) 69 (5): 601–606.
Published: 01 November 1985
...J. Buckley; E. M. Gebruers; W. J. Hall; N. M. B. Harrington 1. Intravenous vasopressin (1–3 μ-units min −1 kg −1 ) had an antidiuretic effect on water-loaded man and also diminished potassium excretion. As noted by others, aspirin (2.4 g) enhanced the antidiuretic effect of vasopressin...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1985) 69 (4): 471–476.
Published: 01 October 1985
...P. J. Grant; J. A. Davies; G. M. Tate; M. Boothby; C. R. M. Prentice 1. Plasma concentrations of vasopressin (aVP) attained under conditions of stress were simulated by infusing four volunteers with 0.25, 0.5, 1.0 and 2.0 pressor units of aVP over 1 h (units/h). Three subjects had all four...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1985) 69 (3): 293–298.
Published: 01 September 1985
...C. Ray; S. L. Carney; A. H. B. Gillies 1. The precise role of prostaglandins in modulating urine concentration and dilution is unclear. Evidence in vitro has recently cast doubt on the accepted theory that renal prostaglandins inhibit the hydro-osmotic effect of vasopressin. 2. Urine clearance...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1985) 69 (2): 231–233.
Published: 01 August 1985
...P. J. T. Drew; J. P. Monson; H. K. Metcalfe; S. J. W. Evans; R. A. Iles; R. D. Cohen 1. The effect of arginine vasopressin (AVP) on ureagenesis was measured in isolated rat hepatocytes with ammonium chloride and l(+)-lactate as substrates. 2. AVP was found to stimulate urea synthesis and the dose...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1985) 68 (6): 647–657.
Published: 01 June 1985
...S. M. Gardiner; T. Bennett 1. Plasma volumes and cardiovascular status were assessed in rats with a congenital deficiency in hypothalamic vasopressin (Brattleboro strain) and in the parent strain (Long Evans), in water-replete and water-deprived states. 2. Water-replete Brattleboro rats were...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1985) 68 (6): 669–674.
Published: 01 June 1985
...P. A. Phillips; B. J. Rolls; J. G. G. Ledingham; J. J. Morton; M. L. Forsling 1. The thirst and plasma vasopressin responses to single-blind controlled intravenous angiotensin II infusions (2-16 ng min −1 kg −1 ) were investigated in ten healthy young men. 2. Thirst and vasopressin secretion were...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1984) 67 (3): 353–358.
Published: 01 September 1984
...P. J. T. Drew; J. N. Barnes; J. M. P. Holly; A. Knight; F. J. Goodwin 1. The effects of a 48 h infusion of arginine vasopressin (AVP) were measured in five separate studies on four normal salt-restricted physicians, in whom fluid retention was prevented. 2. The infusion was associated...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 65 (1): 19–25.
Published: 01 July 1983
...S. M. Gardiner; T. Bennett 1. The effects of naloxone on blood pressure recovery after either rapid arterial haemorrhage or prolonged venous haemorrhage were studied in rats lacking vasopressin (Brattleboro strain) and in control (Long Evans) rats. 2. To produce similar reductions in blood pressure...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 64 (6): 623–627.
Published: 01 June 1983
.... The maximum urine osmolality ( U max .) after an intravenous injection of desamino- d -arginine vasopressin (DDAVP) was also measured. 2. in all the control subjects and six of the patients, the U max. after DDAVP exceeded 700 mosmol/kg. The cyclic AMP responses in these two groups did not differ...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 64 (4): 377–382.
Published: 01 April 1983
...S. M. Gardiner; T. Bennett 1. The effects of isolation on systolic blood pressure, heart rate and fluid and electrolyte balances were studied in rats with a congenital inability to synthesize vasopressin (Brattleboro strain) and in the normal parent strain (Long Evans). 2. There was no significant...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 64 (4): 407–415.
Published: 01 April 1983
... prostaglandin F 2α renin vasopressin © 1983 The Biochemical Society and the Medical Research Society 1983 10 9 1982 16 11 1982 Clinical Science ( 1983) 64,407-4 15 407 Interaction of diuretics and non-steroidal anti-inflammatory drugs in man L. FAVRE, PH. GLASSON, A. RIONDELANDM. B...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (4): 367–372.
Published: 01 October 1982
...Bruce G. Robinson; Phillip Clifton-Bligh; Solomon Posen; Brian J. Morris 1. The oral administration of 2·5 mg of the dopamine (3,4-dihydroxyphenethylamine) agonist bromoergocriptine enhanced the osmotically stimulated rise in plasma [arginine]vasopressin ([Arg]VP) concentrations in five normal...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 289s–292s.
Published: 01 October 1982
...W. W. Blessing; A. F. Sved; D. J. Reis 1. Injection of the neurotoxin kainic acid into the region of the A1 noradrenergic neurons in the caudal ventrolateral medulla of rabbit increases blood pressure by 35 mmHg and plasma vasopressin five fold. 2. After cervical spinal cord transection...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 335s–338s.
Published: 01 October 1982
... system. © 1982 The Biochemical Society and the Medical Research Society 1982 baroreflexes brain angiotensin captopril central blood pressure regulation hypertonic sodium chloride renin-angiotensin system sodium sympathetic nerve activity vasopressin Clinical Science (1982) 63,3359-338s...
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