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Keywords: vitamin D
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Clin Sci (Lond) (2013) 124 (9): 553–566.
Published: 21 January 2013
... evaluating the two principal approaches to renin inhibition, namely direct renin inhibition with aliskiren and inhibition of the (pro)renin receptor. Moreover, the possibilities of renin inhibition and nephroprotection by interventions primarily aiming at non-RAAS targets, such as vitamin D, urocortins...
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Clin Sci (Lond) (2011) 120 (3): 91–97.
Published: 14 October 2010
... circulating factors, like vitamin D, PTH (parathyroid hormone) and FGF23 (fibroblast growth factor 23), are essential for regulation of physiological phosphate balance. Dysregulation of these factors, either alone or in combination, can induce phosphorus imbalance. Recent studies have shown that suppression...
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Clin Sci (Lond) (2010) 119 (3): 111–121.
Published: 28 April 2010
..., parathyroid hormone or vitamin D, a better understanding of the mechanisms of abnormal tissue calcification may lead to development of new therapeutic agents, which could reduce VC and improve cardiovascular outcome in CKD patients. The present review summarizes the following aspects: (i...
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Clin Sci (Lond) (2009) 116 (12): 871.
Published: 14 May 2009
...William B. Grant It has been suggested that pregnant and lactating women require 4000–6000 international units/day of vitamin D [ 4 ]. As VEGF tests are much more expensive than vitamin D supplements and since there are many health benefits of vitamin D, including protection against many types...
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Clin Sci (Lond) (2000) 98 (2): 217–240.
Published: 31 January 2000
... become possible to describe their precise mechanism of action. This review focuses not only on the steroid hormones (oestrogens, corticosteroids, androgens and progesterone), but also on related hormones (vitamin D, thyroid hormone and the retinoids), all of which act via structurally homologous nuclear...
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Clin Sci (Lond) (1990) 78 (3): 295–302.
Published: 01 March 1990
... 9 1989 7 11 1989 © 1990 The Biochemical Society and the Medical Research Society 1990 acetazolamide acid-base balance acidosis calcium metabolism haemodialysis uraemia vitamin D Clinical Science (1990) 78,295-302 295 Severe metabolic acidosis and disturbances of calcium...
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Clin Sci (Lond) (1989) 77 (2): 171–176.
Published: 01 August 1989
... associated with various metabolic myopathies, including osteomalacia. 2. The maximum voluntary contraction (MVC) of the dominant quadriceps and plasma 25-hydroxycholecalciferol [25-(OH)D] were measured in male alcoholics and control subjects to determine whether vitamin D deficiency contributed to proximal...
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Clin Sci (Lond) (1987) 73 (6): 659–664.
Published: 01 December 1987
... for by an increased excretion of vitamin D-derived inactivation products in the faeces. 4. Enhanced hepatic inactivation of 25-hydroxyvitamin D may be important in the development of vitamin D deficiency in primary hyperparathyroidism. 18 5 1987 15 6 1987 © 1970 The Biochemical Society...
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Clin Sci (Lond) (1981) 61 (4): 471–476.
Published: 01 October 1981
...U. Trechsel; C. M. Taylor; J. A. Eisman; J.-P. Bonjour; H. Fleisch 1. Protein-binding assays have been used to measure plasma 1,25-dihydroxy-vitamin D [1,25-(OH) 2 D] as well as 25-hydroxy-vitamin D [25-(OH)D] in rats given 10 mg of phosphorus (P) day −1 kg −1 as ethane-1-hydroxy-1,1-diphosphonate...
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Clin Sci (Lond) (1980) 58 (3): 235–242.
Published: 01 March 1980
... for up to 15 min total exposure. This contrasted with the prolonged increase in plasma 25-(OH)D continuing over several weeks in response to whole-body ultraviolet irradiation. This may indicate that cutaneous synthesis of vitamin D is rapid but limited, and that the considerable rise in plasma 25-(OH)D...
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Clin Sci Mol Med (1974) 46 (4): 433–448.
Published: 01 April 1974
...-HCC. 4. Treatment with phenobarbitone enhanced the excretion of metabolites of radioactive vitamin D 3 in bile. These metabolites were largely water-soluble conjugates of peaks IV, V and VI, which included glucuronides. Peak IV in bile was not identical with 25-HCC. 5. Prolonged treatment...
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Clin Sci (1972) 43 (3): 413–431.
Published: 01 September 1972
...E. Barbara Mawer; Joan Backhouse; Carlene A. Holman; G. A. Lumb; S. W. Stanbury 1. The distribution of vitamin D and its metabolites in human tissues has been studied by the combined use of radioactive cholecalciferol and biological assays of antiricketic activity in tissue extracts. 2. Injected...
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Clin Sci (1972) 42 (4): 515–522.
Published: 01 April 1972
...W. H. Taylor 1. Of 104 patients with renal calculi, 42% gave a history of previous self-medication with multivitamin preparations containing vitamin D, compared with 37% of a control group of fifty-one patients without renal calculi. This difference is not significant. 2. The mean supplemental...
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Clin Sci (1972) 42 (2): 235–241.
Published: 01 February 1972
... of osteoporosis. 4 11 1971 © 1972 The Biochemical Society and the Medical Research Society 1972 parathyroid hormone calcitonin bone calcium osteoporosis vitamin D Clinical Science (1972) 42,235-241. SHORT COMM UNICA TI0 N CALCIUM SHIFT INTO BONE: A CALCITONIN- RESISTANT PRIMARY ACTION O...
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Clin Sci (1972) 42 (1): 113–116.
Published: 01 January 1972
..., an infant with associated kwashiorkor and a child with late onset juvenile rickets. 2. Five children, reinvestigated after 6 weeks of vitamin D treatment, showed highly significant falls in P.T.H. concentration, confirming the functional nature of the secondary hyperparathyroidism. The activity of plasma...