...Paolo Coruzzi; Almerico Novarini; Luisa Musiari; Carlo Ravanetti; Salvatore Ghielmi; Anna Rodella; Alberto Montanari 1. Ten normal subjects were subjected to 2 h water immersion with and without pharmacological dopaminergic blockade with either metoclopramide (group I) or domperidone (group II). 2...

...P. Coruzzi; C. Ravanetti; L. Musiari; A. Biggi; P. P. Vescovi; A. Novarini 1. This study was designed to evaluate variations in plasma β-endorphin, methionine-enkephalin, adrenocorticotropic hormone and serum prolactin in healthy volunteers during head-out water immersion. 2. Water immersion...

...J. P. O'Hare; J. M. Roland; G. Walters; R. J. M. Corrall 1. The renal response to volume expansion produced by water immersion to the neck at 35°C was examined in eight young normotensive uncomplicated insulin-dependent diabetic subjects and in eight matched normal control subjects. 2. Both...

...J. V. Anderson; N. D. Millar; J. P. O'Hare; J. C. MacKenzie; R. J. M. Corrall; S. R. Bloom 1. Thermoneutral water immersion produces a physiological increase of thoracic blood volume, raises central venous pressure and increases urinary sodium excretion by a hitherto ill-understood mechanism. We...

...P. Coruzzi; A. Biggi; L. Musiari; C. Ravanetti; P. P. Vescovi; A. Novarini 1. Natriuresis was studied during water immersion in eight normal subjects either in the absence or in the presence of dopamine blockade by domperidone. 2. Creatinine clearance showed no significant changes; urine flow...

...J. P. O'hare; M. Watson; M. D. Penney; D. Hampton; J. M. Roland; R. J. M. Corrall 1. In 10 normal subjects water immersion to the neck at 35°C produced a highly significant natriuresis and diuresis. 2. Urinary prostaglandin E levels did not change significantly throughout immersion. 3. During...

...P. Coruzzi; A. Biggi; L. Musiari; C. Ravanetti; A. Novarini 1. We studied renin-aldosterone system behaviour in five renovascular hypertensive patients during central hypervolaemia by water immersion to the neck. 2. Water immersion significantly suppressed the high peripheral renin levels...

... handling and aldosterone levels on immersion. 6 4 1981 27 4 1981 © 1981 The Biochemical Society and the Medical Research Society 1981 nephrotic syndrome tubular function urinary chloride urinary sodium water water immersion Renal salt and water handling in water immersion...

... not been assessed fully during volume expansion. Since studies have demonstrated that in normal man the central hypervolaemia induced by water immersion to the neck produces a prompt and profound suppression of plasma renin activity and plasma aldosterone concentration without concomitant alteration...

... volume (VTPC) were compared with the changes induced by water immersion to the neck for 4 h. Serial measurements were made at 30 min intervals in five normal subjects, utilizing a non-invasive rebreathing method with a gas mixture containing 0·5% acetylene, 0·3% C180, 10% He, 21% O 2 and 68·2% N 2 . 2...

... increased VC and D LCO ; pulmonary compliance and flow/volume curves did not alter significantly. 3. It is concluded that peripheral venous occlusion produces these effects by altering intrathoracic blood volume. Water immersion reduces TLC, mainly from the hydrostatic pressure, and VC is reduced from both...

...M. Epstein; D. C. Duncan; L. M. Fishman 1. The effects of 4–6 h of water immersion on the renal excretion of water and electrolytes were studied in thirteen normal male subjects in balance on a constant diet containing 150 mEq of Na and 100 mEq of K per day. Each subject was studied during...