... in patients with alcoholic liver disease. 27 8 1992 9 9 1992 © 1993 The Biochemical Society and the Medical Research Society 1993 alcohol kinetics liver stable isotope zinc Clinical Science (1993) 84, 113-1 17 (Printed in Great Britain) I I 3 Studies of human zinc kinetics using...

... groups to receive either a standard diet or one supplemented with zinc. From each group, animals were killed at weeks 3 and 18 of the experiment for histological and biochemical assessments which included hepatic lipid peroxide and collagen concentrations and plasma zinc concentration as well...

...J. A. Taylor; J. Acharya; T. C. Pearson; R. P. H. Thompson 1. The deformability of erythrocytes from patients with sickle-cell anaemia was measured with a St George's blood filtrometer at a range of oxygen partial pressures and at four levels of zinc loading. 2. When incubated in buffered saline...

...Helen F. Goode; Jerry Kelleher; Barry E. Walker; Richard I. Hall; Pierre J. Guillou 1. The zinc status of surgical patients with and without gastrointestinal cancer was studied. 2. Plasma zinc was lowest in patients with cancer concurrent with depressed plasma albumin concentrations. 3...

...C. C. Ainley; J. Cason; L. K. Carlsson; B. M. Slavin; R. P. H. Thompson 1. The zinc contents of plasma, erythrocytes, polymorphonuclear leucocytes and mononuclear leucocytes from 18 normal control subjects, 31 patients with Crohn's disease and 15 patients with ulcerative colitis were measured. 2...

...S. G. Jacobson; N. J. Meadows; P. W. N. Keeling; W. D. Mitchell; R. P. H. Thompson 1. Cats fed for 4 months with a diet with less than 7 p.p.m. zinc developed tissue zinc depletion, as judged by reduced muscle zinc content. 2. Dark adapted electroretinogram (ERG) thresholds became elevated in zinc...

...Michael W. J. Davie; Ralph R. Abraham; Belinda Hewins; Victor Wynn 1. The effects of dietary carbohydrate (CHO) content and of tri-iodothyronine (T 3 ) administration on calcium, zinc and phosphate balances and on urinary hydroxyproline output were examined in eight obese subjects undergoing...

...Karen Simmer; R. P. H. Thompson 1. The levels of zinc in plasma, erythrocytes, polymorphonuclear (PMN) and mononuclear (MN) white cells were measured after delivery in women giving birth to appropriate-for-gestational-age (AGA) babies (group I mothers), or small-for-gestational-age (SGA) babies...

... porphyria zinc clinical Science (1983) 65, 423-428 423 Decreased liver 6-aminolaevulinate dehydratase activity in porphyria cutanea tarda and in alcoholism MASAO KONDO, GUMPEI URATA A N D YOSHITAKA SHIMIZU* Department of Nutrition and Biochemistry, The Institute of Public Health, Tokyo, and *Department...

...Peter R. Mills; Gordon S. Fell; Rodney G. Bessent; Lesley M. Nelson; Robin I. Russell 1. Zinc metabolism was studied in 11 patients with alcoholic cirrhosis and 13 healthy volunteers using the isotope tracer 65 Zn. 2. Intestinal absorption, whole-body content and total daily elimination of zinc...

...P. W. N. Keeling; J. O'Day; W. Ruse; R. P. H. Thompson 1. In nine patients with chronic liver disease photoreceptor function was tested, by measurement of the B-wave amplitude of dark adaptation by electroretinography, and the leucocyte content and plasma concentration of zinc were determined. 2...

...P. W. N. Keeling; W. Ruse; J. Bull; B. Hannigan; R. P. H. Thompson 1. 65 Zn was injected intravenously during transjugular liver biopsy and, from simultaneous hepatic and peripheral venous blood samples, hepatointestinal 65 Zn extraction was calculated. Hepatic zinc content was measured in biopsy...

...R. B. Jones; P. W. N. Keeling; P. J. Hilton; R. P. H. Thompson 1. A significant correlation between leucocyte and muscle zinc contents was observed in control patients and in patients with generalized diseases. 2. As muscle contains a large proportion of the whole-body zinc, it is suggested...

...J. Patrick; J. Michael; M. N. Golden; B. E. Golden; P. J. Hilton 1. In a preparation of human leucocytes maintained in tissue culture fluid, increasing the extracellular zinc concentration leads to a significant increase in both ouabain-sensitive sodium efflux and in sodium influx. 2. Cell water...

...E. Giroux; P. J. Schechter; Josiane Schoun 1. Distribution of zinc between the metalloprotein α 2 -macroglobulin and albumin was determined in samples of serum obtained from twenty-three women in their third trimester of pregnancy and eighteen women who were not pregnant. 2. The decrease observed...

...G. S. Thind; Grace M. Fischer 1. Plasma cadmium and zinc were determined by atomic absorption spectrophotometry in inferior venal caval or peripheral venous blood in thirty hypertensive patients and fifteen normal subjects. 2. The mean plasma cadmium in hypertensive patients was significantly...

...Gurdarshan S. Thind; Grace M. Fischer 1. Plasma zinc (μg/100 ml) was determined by atomic absorption spectrophotometry in ninety renal venous, inferior vena caval or peripheral venous specimens obtained from fifteen normal control subjects and thirty hypertensive patients, none of whom had renal...

...J. M. Aitken; R. Lindsay; D. McKay Hart 1. The specific gravity and zinc concentration of plasma obtained during fasting were measured in pre- and post-menopausal women. A number of the latter had been taking 20–40 μg of mestranol daily for at least 1 year. 2. A highly significant correlation...