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Editors' pick of research highlights published in the Biochemical Journal in 2018 & 2019
The Biochemical Journal is delighted to share this Editors' pick of content, which has been selected by the Editorial Board to highlight some of the best original research published in the journal in 2018 and 2019. The Biochemical Journal would like to thank all authors who contributed their excellent research and to thank the Editorial Board for selecting this collection to share with our readers.
Belén Fernández; Antonio Jesús Lara Ordóñez; Elena Fdez; Eugénie Mutez; Thomas Comptdaer; Coline Leghay; Alexandre Kreisler; Clémence Simonin; Laurine Vandewynckel; Luc Defebvre; Alain Destée; Séverine Bleuse; Jean-Marc Taymans; Marie-Christine Chartier-Harlin; Sabine Hilfiker
Cecilia Jönsson; Ana P. Castor Batista; Preben Kjølhede; Peter Strålfors
Jennyfer Martínez; Doménica Tarallo; Laura Martínez-Palma; Sabina Victoria; Mariana Bresque; Sebastián Rodríguez-Bottero; Inés Marmisolle; Carlos Escande; Patricia Cassina; Gabriela Casanova; Mariela Bollati-Fogolín; Caroline Agorio; María Moreno; Celia Quijano
Structural basis for histone H3K4me3 recognition by the N-terminal domain of the PHD finger protein Spp1
Available to Purchase
Chao He; Ning Liu; Dongya Xie; Yanhong Liu; Yazhong Xiao; Fudong Li
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells
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Mam Y. Mboge; Zhijuan Chen; Daniel Khokhar; Alyssa Wolff; Lingbao Ai; Coy D. Heldermon; Murat Bozdag; Fabrizio Carta; Claudiu T. Supuran; Kevin D. Brown; Robert McKenna; Christopher J. Frost; Susan C. Frost
Calcium–calmodulin gating of a pH-insensitive isoform of connexin43 gap junctions
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Siyu Wei; Christian Cassara; Xianming Lin; Richard D. Veenstra
Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)
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Apirat Chaikuad; Sebastian E. Koschade; Alexandra Stolz; Katarina Zivkovic; Christian Pohl; Shabnam Shaid; Huiyu Ren; Lester J. Lambert; Nicholas D.P. Cosford; Christian H. Brandts; Stefan Knapp
Structural basis for the bypass of the major oxaliplatin–DNA adducts by human DNA polymerase η
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Hala Ouzon-Shubeita; Meghan Baker; Myong-Chul Koag; Seongmin Lee
Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy
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Jiangbo Wang; Xiu-rong Ren; Hailan Piao; Shengli Zhao; Takuya Osada; Richard T. Premont; Robert A. Mook, Jr; Michael A. Morse; Herbert Kim Lyerly; Wei Chen
Kinase activity of mutant LRRK2 manifests differently in hetero-dimeric vs. homo-dimeric complexes
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Emmanouela Leandrou; Eliana Markidi; Anna Memou; Katerina Melachroinou; Elisa Greggio; Hardy J. Rideout
The oxidation of dehydroascorbic acid and 2,3-diketogulonate by distinct reactive oxygen species
Open Access
Rebecca A. Dewhirst; Stephen C. Fry
Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity
Open Access
Elaine C. Thomas; Sharon C. Hook; Alexander Gray; Alexandra Chadt; David Carling; Hadi Al-Hasani; Kate J. Heesom; D. Grahame Hardie; Jeremy M. Tavaré
Dominic P. Byrne; Yong Li; Pawin Ngamlert; Krithika Ramakrishnan; Claire E. Eyers; Carrow Wells; David H. Drewry; William J. Zuercher; Neil G. Berry; David G. Fernig; Patrick A. Eyers
Yugo Tsuchiya; Alexander Zhyvoloup; Jovana Baković; Naam Thomas; Bess Yi Kun Yu; Sayoni Das; Christine Orengo; Clare Newell; John Ward; Giorgio Saladino; Federico Comitani; Francesco L. Gervasio; Oksana M. Malanchuk; Antonina I. Khoruzhenko; Valeriy Filonenko; Sew Yeu Peak-Chew; Mark Skehel; Ivan Gout
Rafeeq Mir; Francesca Tonelli; Pawel Lis; Thomas Macartney; Nicole K. Polinski; Terina N. Martinez; Meng-Yun Chou; Andrew J.M. Howden; Theresa König; Christoph Hotzy; Ivan Milenkovic; Thomas Brücke; Alexander Zimprich; Esther Sammler; Dario R. Alessi
Inhibition of FOXO1 transcription factor in primary human adipocytes mimics the insulin-resistant state of type 2 diabetes
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Meenu R. Rajan; Elin Nyman; Cecilia Brännmark; Charlotta S. Olofsson; Peter Strålfors
Meng Yuan; Iain W. McNae; Yiyuan Chen; Elizabeth A. Blackburn; Martin A. Wear; Paul A.M. Michels; Linda A. Fothergill-Gilmore; Ted Hupp; Malcolm D. Walkinshaw
A transcription factor network represses CFTR gene expression in airway epithelial cells
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Michael J. Mutolo; Shih-Hsing Leir; Sara L. Fossum; James A. Browne; Ann Harris
P62/SQSTM1 is a novel leucine-rich repeat kinase 2 (LRRK2) substrate that enhances neuronal toxicity
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Alexia F. Kalogeropulou; Jing Zhao; Marc F. Bolliger; Anna Memou; Shreya Narasimha; Tyler P. Molitor; William H. Wilson; Hardy J. Rideout; R. Jeremy Nichols
Adhesion/growth-regulatory galectins tested in combination: evidence for formation of hybrids as heterodimers
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Michelle C. Miller; Anna-Kristin Ludwig; Kanin Wichapong; Herbert Kaltner; Jürgen Kopitz; Hans-Joachim Gabius; Kevin H. Mayo
