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Towards systems biochemistry

Guest edited by Professor Stanislav Y. Shvartsman and Professor Kazuhiro Aoki

Systems Biology has opened new frontiers in the life sciences, investigating multilayers of biological complexity in governing gene regulatory networks, metabolic pathways, and cell signaling. Furthermore, emerging technologies such as next-generation sequencing, CRISPR/Cas9-mediated genome editing, and deep-learning have allowed the collection of data more deeply, comprehensively, and quantitatively. However, we are still far from a sufficient understanding of regulatory mechanisms underlying complicated cellular and multicellular behaviours as a system.

This Biochemical Journal collection, Towards Systems Biochemistry, comprises review articles and research papers providing a systems understanding of regulatory mechanisms in molecular and cellular biology, including gene regulatory networks, metabolic pathways and cell signalling.

We would like to thank all the authors for their excellent contributions, and we hope you enjoy reading this special collection.

Collection image from Tany et al. (2022) https://doi.org/10.1042/BCJ20220021

Special Collection Image
Atsushi Mukaiyama; Yoshihiko Furuike; Eiki Yamashita; Shuji Akiyama
DOI: 10.1042/BCJ20210544
Lorenza A. D’Alessandro; Ursula Klingmüller; Marcel Schilling
DOI: 10.1042/BCJ20210548
Siddhartha G. Jena; Alexander G. Goglia; Barbara E. Engelhardt
DOI: 10.1042/BCJ20220053
Atsushi Mochizuki
DOI: 10.1042/BCJ20210545
Ryosuke Tany; Yuhei Goto; Yohei Kondo; Kazuhiro Aoki
DOI: 10.1042/BCJ20220021
Satoshi Ohno; Saori Uematsu; Shinya Kuroda
DOI: 10.1042/BCJ20210596
Michael Batie; Julianty Frost; Dilem Shakir; Sonia Rocha
DOI: 10.1042/BCJ20220008
Michael Batie; Niall S. Kenneth; Sonia Rocha
DOI: 10.1042/BCJ20210554
Masatoshi Haga; Mariko Okada
DOI: 10.1042/BCJ20210547
John J. Tyson
DOI: 10.1042/BCJ20210370
Tsuyoshi Hirashima
DOI: 10.1042/BCJ20210557
Lachlan J. Munro; Douglas B. Kell
DOI: 10.1042/BCJ20210535
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