Integrated Structural Biology
Recent developments in small-angle X-ray scattering and hybrid method approaches for biomacromolecular solutions
Capturing dynamic conformational shifts in protein–ligand recognition using integrative structural biology in solution
Cryo-STX projection image showing a parasitophorous vacuole (yellow) within a human fibroblast cell, containing four Toxoplasma gondii parasites (membranes in cyan, nuclei in red and rhoptries in green). In this issue of Emerging Topics in Life Sciences, Harkiolaki et al. describe the use of Cryo-soft X-ray tomography to explore the ultrastructure of whole cells. Image kindly provided by Professor Helen Saibil (Birkbeck College, London, U.K.). For further details, see pages 81–92.