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Articles

AI in drug design: evolution or revolution?

Open Access
Darren V. S. Green
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2025) ETLS20240005.
https://doi.org/10.1042/ETLS20240005
Published: 17 June 2025
View articletitled, AI in drug design: evolution or revolution?
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Articles

Advances in the discovery and analyses of human tandem repeats

Available to Purchase
Mark J.P. Chaisson, Arvis Sulovari, Paul N. Valdmanis, Danny E. Miller, Evan E. Eichler
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2023) 7 (3): 361–381.
https://doi.org/10.1042/ETLS20230074
Published: 31 October 2023
View articletitled, Advances in the discovery and analyses of human tandem repeats
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Articles

Exploring protein symmetry at the RCSB Protein Data Bank

Open Access
Jose M. Duarte, Shuchismita Dutta, David S. Goodsell, Stephen K. Burley
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2022) 6 (3): 231–243.
https://doi.org/10.1042/ETLS20210267
Published: 08 July 2022
View articletitled, Exploring protein symmetry at the RCSB Protein Data Bank
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Articles

Applications of cell- and tissue-specific ‘omics to improve plant productivity

Open Access
Bhavna Hurgobin, Mathew G. Lewsey
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2022) 6 (2): 163–173.
https://doi.org/10.1042/ETLS20210286
Published: 16 March 2022
View articletitled, Applications of cell- and tissue-specific ‘omics to improve plant productivity
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Articles

Artificial intelligence, machine learning, and deep learning for clinical outcome prediction

Open Access
Rowland W. Pettit, Robert Fullem, Chao Cheng, Christopher I. Amos
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (6): 729–745.
https://doi.org/10.1042/ETLS20210246
Published: 20 December 2021
View articletitled, Artificial intelligence, machine learning, and deep learning for clinical outcome prediction
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Includes: Supplementary data
Articles

From imaging a single cell to implementing precision medicine: an exciting new era

Open Access
Loukia G. Karacosta
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (6): 837–847.
https://doi.org/10.1042/ETLS20210219
Published: 10 December 2021
View articletitled, From imaging a single cell to implementing precision medicine: an exciting new era
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Articles

Artificial intelligence, molecular subtyping, biomarkers, and precision oncology

Open Access
John Paul Shen
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (6): 747–756.
https://doi.org/10.1042/ETLS20210212
Published: 09 December 2021
View articletitled, Artificial intelligence, molecular subtyping, biomarkers, and precision oncology
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Articles

Applied machine learning in Alzheimer's disease research: omics, imaging, and clinical data

Open Access
Ziyi Li, Xiaoqian Jiang, Yizhuo Wang, Yejin Kim
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (6): 765–777.
https://doi.org/10.1042/ETLS20210249
Published: 09 December 2021
View articletitled, Applied machine learning in Alzheimer's disease research: omics, imaging, and clinical data
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Includes: Supplementary data
Articles

Common computational tools for analyzing CRISPR screens

Open Access
Medina Colic, Traver Hart
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (6): 779–788.
https://doi.org/10.1042/ETLS20210222
Published: 09 December 2021
View articletitled, Common computational tools for analyzing CRISPR screens
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Articles

Artificial intelligence unifies knowledge and actions in drug repositioning

Available to Purchase
Zheng Yin, Stephen T. C. Wong
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (6): 803–813.
https://doi.org/10.1042/ETLS20210223
Published: 09 December 2021
View articletitled, Artificial intelligence unifies knowledge and actions in drug repositioning
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Articles

Radiomics, deep learning and early diagnosis in oncology

Open Access
Peng Wei
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (6): 829–835.
https://doi.org/10.1042/ETLS20210218
Published: 07 December 2021
View articletitled, Radiomics, deep learning and early diagnosis in oncology
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Articles

It takes guts to learn: machine learning techniques for disease detection from the gut microbiome

Open Access
Kristen D. Curry, Michael G. Nute, Todd J. Treangen
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (6): 815–827.
https://doi.org/10.1042/ETLS20210213
Published: 15 November 2021
View articletitled, It takes guts to learn: machine learning techniques for disease detection from the gut microbiome
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Articles

Graph representation learning for structural proteomics

Open Access
Romanos Fasoulis, Georgios Paliouras, Lydia E. Kavraki
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (6): 789–802.
https://doi.org/10.1042/ETLS20210225
Published: 19 October 2021
View articletitled, Graph representation learning for structural proteomics
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Articles

Practical considerations for delivering on the sustainability promise of fermentation-based biomanufacturing

Open Access
David Lips
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 711–715.
https://doi.org/10.1042/ETLS20210129
Published: 08 September 2021
View articletitled, Practical considerations for delivering on the sustainability promise of fermentation-based biomanufacturing
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Articles

Bioinformatics approach to spatially resolved transcriptomics

Available to Purchase
Ivan Krešimir Lukić
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 669–674.
https://doi.org/10.1042/ETLS20210131
Published: 09 August 2021
View articletitled, Bioinformatics approach to spatially resolved transcriptomics
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Articles

Interpretation of DNA data within the context of UK forensic science — evaluation

Open Access
Roberto Puch-Solis, Susan Pope
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (3): 405–413.
https://doi.org/10.1042/ETLS20200340
Published: 24 May 2021
View articletitled, Interpretation of DNA data within the context of UK forensic science — evaluation
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Articles

Revolutionizing enzyme engineering through artificial intelligence and machine learning

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Nitu Singh, Sunny Malik, Anvita Gupta, Kinshuk Raj Srivastava
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (1): 113–125.
https://doi.org/10.1042/ETLS20200257
Published: 09 April 2021
View articletitled, Revolutionizing enzyme engineering through artificial intelligence and machine learning
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Articles

Remodelling structure-based drug design using machine learning

Available to Purchase
Shubhankar Dutta, Kakoli Bose
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (1): 13–27.
https://doi.org/10.1042/ETLS20200253
Published: 07 April 2021
View articletitled, Remodelling structure-based drug design using machine learning
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Articles

An overview of the recent advances in cryo-electron microscopy for life sciences

Available to Purchase
Anshul Assaiya, Ananth Prasad Burada, Surbhi Dhingra, Janesh Kumar
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (1): 151–168.
https://doi.org/10.1042/ETLS20200295
Published: 24 March 2021
View articletitled, An overview of the recent advances in cryo-electron microscopy for life sciences
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Articles

Mass spectrometry based untargeted metabolomics for plant systems biology

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Sophie Alvarez, Michael J. Naldrett
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (2): 189–201.
https://doi.org/10.1042/ETLS20200271
Published: 11 March 2021
View articletitled, Mass spectrometry based untargeted metabolomics for plant systems biology
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Articles

High-throughput image segmentation and machine learning approaches in the plant sciences across multiple scales

Available to Purchase
Eli Buckner, Haonan Tong, Chanae Ottley, Cranos Williams
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (2): 239–248.
https://doi.org/10.1042/ETLS20200273
Published: 04 March 2021
View articletitled, High-throughput image segmentation and machine learning approaches in the plant sciences across multiple scales
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Articles

Rated-M for mesocosm: allowing the multimodal analysis of mature root systems in 3D

Open Access
Tyler Dowd, Samuel McInturf, Mao Li, Christopher N. Topp
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (2): 249–260.
https://doi.org/10.1042/ETLS20200278
Published: 08 February 2021
View articletitled, Rated-M for mesocosm: allowing the multimodal analysis of mature root systems in 3D
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Articles

Multiscale plant modeling: from genome to phenome and beyond

Open Access
Megan L. Matthews, Amy Marshall-Colón
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (2): 231–237.
https://doi.org/10.1042/ETLS20200276
Published: 05 February 2021
View articletitled, Multiscale plant modeling: from genome to phenome and beyond
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Articles

Optimal invasive species surveillance in the real world: practical advances from research

Open Access
Frank H. Koch, Denys Yemshanov, Robert G. Haight, Chris J.K. MacQuarrie, Ning Liu, Robert Venette, Krista Ryall
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (5): 513–520.
https://doi.org/10.1042/ETLS20200305
Published: 26 November 2020
View articletitled, Optimal invasive species surveillance in the real world: practical advances from research
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Articles

Modelling for risk and biosecurity related to forest health

Available to Purchase
Christelle Robinet, Robbert van den Dool, Dorian Collot, Jacob C. Douma
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (5): 485–495.
https://doi.org/10.1042/ETLS20200062
Published: 04 September 2020
View articletitled, Modelling for risk and biosecurity related to forest health
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Articles

Conserved principles of transcriptional networks controlling metabolic flexibility in archaea

Open Access
Amy K. Schmid
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2018) 2 (4): 659–669.
https://doi.org/10.1042/ETLS20180036
Published: 14 December 2018
View articletitled, Conserved principles of transcriptional networks controlling metabolic flexibility in archaea
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Articles

Mechanobiology: protein refolding under force

Available to Purchase
Ionel Popa, Ronen Berkovich
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2018) 2 (5): 687–699.
https://doi.org/10.1042/ETLS20180044
Published: 14 November 2018
View articletitled, Mechanobiology: protein refolding under force
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Articles

Genome size evolution in the Archaea

Open Access
Siri Kellner, Anja Spang, Pierre Offre, Gergely J. Szöllősi, Celine Petitjean, Tom A. Williams
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2018) 2 (4): 595–605.
https://doi.org/10.1042/ETLS20180021
Published: 14 November 2018
View articletitled, Genome size evolution in the Archaea
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Articles

Cancer immune resistance: can theories converge?

Open Access
Rongze Lu, Tolga Turan, Josue Samayoa, Francesco M. Marincola
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2017) 1 (5): 411–419.
https://doi.org/10.1042/ETLS20170060
Published: 12 December 2017
View articletitled, Cancer immune resistance: can theories converge?
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Articles

Integrating the whole from the sum of the parts: vignettes in computational biology

Available to Purchase
Jeffrey Skolnick
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2017) 1 (3): 241–243.
https://doi.org/10.1042/ETLS20170137
Published: 14 November 2017
View articletitled, Integrating the whole from the sum of the parts: vignettes in computational biology
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Articles

Computational biology: deep learning

Open Access
William Jones, Kaur Alasoo, Dmytro Fishman, Leopold Parts
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2017) 1 (3): 257–274.
https://doi.org/10.1042/ETLS20160025
Published: 14 November 2017
View articletitled, Computational biology: deep learning
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Articles

Big knowledge from big data in functional genomics

Open Access
Chris P. Ponting
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2017) 1 (3): 245–248.
https://doi.org/10.1042/ETLS20170129
Published: 14 November 2017
View articletitled, Big knowledge from big data in functional genomics
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Articles

RNA structure prediction: from 2D to 3D

Available to Purchase
Bernhard C. Thiel, Christoph Flamm, Ivo L. Hofacker
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2017) 1 (3): 275–285.
https://doi.org/10.1042/ETLS20160027
Published: 15 September 2017
View articletitled, RNA structure prediction: from 2D to 3D
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