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Articles

Manufacturing of AAV vectors: translational challenges from development to industrialisation

Available to Purchase
Tony Hitchcock
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 725–728.
https://doi.org/10.1042/ETLS20210179
Published: 10 November 2021
View article titled, Manufacturing of AAV vectors: translational challenges from development to industrialisation
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Articles

Targetable nano-delivery vehicles to deliver anti-bacterial small acid-soluble spore protein (SASP) genes

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Anne M. L. Barnard, James A. Cass
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 637–641.
https://doi.org/10.1042/ETLS20210147
Published: 01 November 2021
View article titled, Targetable nano-delivery vehicles to deliver anti-bacterial small acid-soluble spore protein (SASP) genes
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Articles

Therapeutic cancer vaccines: reasons to believe

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Jonathan D. Moore
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 591–595.
https://doi.org/10.1042/ETLS20210205
Published: 08 September 2021
View article titled, Therapeutic cancer vaccines: reasons to believe
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Articles

Mesenchymal stromal cells: what have we learned so far about their therapeutic potential and mechanisms of action?

Open Access
Francesco Amadeo, Katherine Trivino Cepeda, James Littlewood, Bettina Wilm, Arthur Taylor, Patricia Murray
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (4): 549–562.
https://doi.org/10.1042/ETLS20210013
Published: 08 September 2021
View article titled, Mesenchymal stromal cells: what have we learned so far about their therapeutic potential and mechanisms of action?
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Articles

Stem cells and regenerative medicine in sport science

Open Access
Claire E. Stewart
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (4): 563–573.
https://doi.org/10.1042/ETLS20210014
Published: 27 August 2021
View article titled, Stem cells and regenerative medicine in sport science
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Articles

Remyelination: what are the prospects for regenerative therapies in multiple sclerosis?

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Jonathan D. Moore
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 705–709.
https://doi.org/10.1042/ETLS20210164
Published: 20 August 2021
View article titled, Remyelination: what are the prospects for regenerative therapies in multiple sclerosis?
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Articles

ImmTOR TM to amplify the efficacy and reduce immunogenicity of biologics

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Carsten Brunn, Takashi Kei Kishimoto
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 597–600.
https://doi.org/10.1042/ETLS20210127
Published: 13 August 2021
View article titled, ImmTOR TM to amplify the efficacy and reduce immunogenicity of biologics
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Articles

Mesenchymal stem cells from biology to therapy

Open Access
David Kuntin, Paul Genever
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (4): 539–548.
https://doi.org/10.1042/ETLS20200303
Published: 06 August 2021
View article titled, Mesenchymal stem cells from biology to therapy
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Articles

RNA-binding proteins modulate drug sensitivity of cancer cells

Open Access
Oliver Rogoyski, André P. Gerber
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 681–685.
https://doi.org/10.1042/ETLS20210193
Published: 30 July 2021
View article titled, RNA-binding proteins modulate drug sensitivity of cancer cells
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Articles

‘EngNT’ — Engineering live neural tissue for nerve replacement

Open Access
James B. Phillips
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 699–703.
https://doi.org/10.1042/ETLS20210085
Published: 23 July 2021
View article titled, ‘EngNT’ — Engineering live neural tissue for nerve replacement
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Articles

Transthyretin-mediated protein and peptide oligomerization for enhanced target clustering

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Daniel Yoo, Kenneth W. Walker
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 665–668.
https://doi.org/10.1042/ETLS20210028
Published: 20 July 2021
View article titled, Transthyretin-mediated protein and peptide oligomerization for enhanced target clustering
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Articles

Antimicrobial immunotherapeutics: past, present and future

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Derry K Mercer, Marie-Louise Francis, Douglas Fraser-Pitt
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 609–628.
https://doi.org/10.1042/ETLS20200348
Published: 01 July 2021
View article titled, Antimicrobial immunotherapeutics: past, present and future
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Articles

What role for cysteamine in the defence against infection?

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Douglas Fraser-Pitt, Derry Mercer
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 629–635.
https://doi.org/10.1042/ETLS20200351
Published: 24 May 2021
View article titled, What role for cysteamine in the defence against infection?
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Articles

Affinity maturation: highlights in the application of in vitro strategies for the directed evolution of antibodies

Open Access
Denice T.Y. Chan, Maria A.T. Groves
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2021) 5 (5): 601–608.
https://doi.org/10.1042/ETLS20200331
Published: 04 March 2021
View article titled, Affinity maturation: highlights in the application of in vitro strategies for the directed evolution of antibodies
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Articles

Nanotheranostic agents for neurodegenerative diseases

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Parasuraman Padmanabhan, Mathangi Palanivel, Ajay Kumar, Domokos Máthé, George K. Radda, Kah-Leong Lim, Balázs Gulyás
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (6): 645–675.
https://doi.org/10.1042/ETLS20190141
Published: 15 December 2020
View article titled, Nanotheranostic agents for neurodegenerative diseases
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Articles

Approaches to treating tuberculosis by encapsulating metal ions and anti-mycobacterial drugs utilizing nano- and microparticle technologies

Open Access
Khaled H. Alzahabi, Omar Usmani, Theoni K. Georgiou, Mary P. Ryan, Brian D. Robertson, Teresa D. Tetley, Alexandra E. Porter
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (6): 581–600.
https://doi.org/10.1042/ETLS20190154
Published: 14 December 2020
View article titled, Approaches to treating tuberculosis by encapsulating metal ions and anti-mycobacterial drugs utilizing nano- and microparticle technologies
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Articles

Biotechnology, nanotechnology and medicine

Open Access
Sonia Contera, Jorge Bernardino de la Serna, Teresa D. Tetley
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (6): 551–554.
https://doi.org/10.1042/ETLS20200350
Published: 09 December 2020
View article titled, Biotechnology, nanotechnology and medicine
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Articles

Gold nanomaterials in the management of lung cancer

Open Access
Ainoa Guinart, Hannah L. Perry, James D. E. T. Wilton-Ely, Teresa D. Tetley
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (6): 627–643.
https://doi.org/10.1042/ETLS20200332
Published: 03 December 2020
View article titled, Gold nanomaterials in the management of lung cancer
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Articles

Best served small: nano battles in the war against wound biofilm infections

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Joanna Shepherd
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (6): 567–580.
https://doi.org/10.1042/ETLS20200155
Published: 03 December 2020
View article titled, Best served small: nano battles in the war against wound biofilm infections
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Articles

Nano-vehicles give new lease of life to existing antimicrobials

Open Access
Ioanna Mela, Clemens F. Kaminski
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (6): 555–566.
https://doi.org/10.1042/ETLS20200153
Published: 01 December 2020
View article titled, Nano-vehicles give new lease of life to existing antimicrobials
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Articles

Novel therapies using cell sheets engineered from allogeneic mesenchymal stem/stromal cells

Open Access
Makoto Kondo, Sumako Kameishi, David W. Grainger, Teruo Okano
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (6): 677–689.
https://doi.org/10.1042/ETLS20200151
Published: 24 November 2020
View article titled, Novel therapies using cell sheets engineered from allogeneic mesenchymal stem/stromal cells
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Articles

Emerging nanomaterials for dental treatments

Open Access
Zi Hong Mok, Gordon Proctor, Maya Thanou
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (6): 613–625.
https://doi.org/10.1042/ETLS20200195
Published: 17 November 2020
View article titled, Emerging nanomaterials for dental treatments
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Articles

Fremanezumab: a disease-specific option for the preventive treatment of migraine, including difficult-to-treat migraine

Open Access
Deborah I. Friedman, Joshua M. Cohen
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (2): 179–190.
https://doi.org/10.1042/ETLS20200018
Published: 24 August 2020
View article titled, Fremanezumab: a disease-specific option for the preventive treatment of migraine, including difficult-to-treat migraine
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Articles

Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD

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Hana M. Odeh, James Shorter
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (3): 293–305.
https://doi.org/10.1042/ETLS20190167
Published: 08 July 2020
View article titled, Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD
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Articles

Recent developments in antibody therapeutics against prion disease

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Karl Frontzek, Adriano Aguzzi
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (2): 169–173.
https://doi.org/10.1042/ETLS20200002
Published: 07 July 2020
View article titled, Recent developments in antibody therapeutics against prion disease
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Articles

Mitochondrial donation — hope for families with mitochondrial DNA disease

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Lyndsey Craven, Julie L. Murphy, Doug M. Turnbull
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (2): 151–154.
https://doi.org/10.1042/ETLS20190196
Published: 23 June 2020
View article titled, Mitochondrial donation — hope for families with mitochondrial DNA disease
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Articles

Therapeutics—how to treat phase separation-associated diseases

Open Access
Richard John Wheeler
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2020) 4 (3): 331–342.
https://doi.org/10.1042/ETLS20190176
Published: 04 May 2020
View article titled, Therapeutics—how to treat phase separation-associated diseases
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Articles

Chronic Chagas cardiomyopathy: a therapeutic challenge and future strategies

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Juan D. Maya, Michel Lapier, Christian Castillo, Ulrike Kemmerling, Carolina Campos-Estrada, Rodrigo López-Muñoz
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2017) 1 (6): 579–584.
https://doi.org/10.1042/ETLS20170109
Published: 22 December 2017
View article titled, Chronic Chagas cardiomyopathy: a therapeutic challenge and future strategies
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Articles

Drug resistance in protozoan parasites

Open Access
Harry P. de Koning
Journal: Emerging Topics in Life Sciences
Emerg Top Life Sci (2017) 1 (6): 627–632.
https://doi.org/10.1042/ETLS20170113
Published: 22 December 2017
View article titled, Drug resistance in protozoan parasites
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