...Mary Anne Panoyan; Frank R. Wendt The human genome contains numerous genetic polymorphisms contributing to different health and disease outcomes. Tandem repeat (TR) loci are highly polymorphic yet under-investigated in large genomic studies, which has prompted research efforts to identify novel...

... to remediate perturbed ecosystems. Recent advances in (meta)proteomics and (community) metabolomics have provided a link between genomic expression and functional characterisation of ecosystem taxa [ 44 ]. This provides valuable insight into their in situ metabolism and function, under a range of biotic...

...Bhavna Hurgobin; Mathew G. Lewsey ‘Omics describes a broad collection of research tools and techniques that enable researchers to collect data about biological systems at a very large, or near-complete, scale. These include sequencing of individual and community genomes (genomics, metagenomics...

... past, various multi-omics’ standalone and integrated studies have been conducted to examine the molecular mechanisms of complex disorders, which include but are not limited to the implementation of several bench protocols and computational approaches, involving genomics, transcriptomics, metabolomics...

... characterization of patient profiles together with more response data for many patients can help generate complex predictive models of response to therapy. These models can be further tested in vivo using patient derived mouse xenograft models and eventually in patients. AI genomics personalized medicine...

... polymorphism) genotyping, quickly and cheaply establishing a person's genotype at thousands of points across the genome [ 1 ]. SNP genotyping, however, is a highly inaccurate method for detecting very rare variants: recent research comparing SNP genotyping data with exome sequencing data for participants...

...Mariana A. Silva Artur; Maria-Cecília D. Costa; Jill M. Farrant; Henk W.M. Hilhorst Plants being sessile organisms are well equipped genomically to respond to environmental stressors peculiar to their habitat. Evolution of plants onto land was enabled by the ability to tolerate extreme water loss...

... regions, such as the Western Pacific, corals may not be more resistant and resilient to natural and anthropogenic disturbances [ 15 ]. adaptive response climate genomics governance reefs transcriptomics Scleractinian corals — otherwise known as hard or reef-building corals — arose...

...Nicholas P. Robinson; Siri Kellner; Anja Spang; Pierre Offre; Gergely J. Szöllősi; Celine Petitjean; Tom A. Williams What determines variation in genome size, gene content and genetic diversity at the broadest scales across the tree of life? Much of the existing work contrasts eukaryotes...