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Keywords: metabolic engineering
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Emerg Top Life Sci (2018) 2 (3): 333–335.
Published: 26 October 2018
...Mattheos A.G. Koffas; Robert J. Linhardt; Mattheos A.G. Koffas; Robert J. Linhardt The application of metabolic engineering to the production of glycans and glycoconjugates is the subject of this of Emerging Topics in Life Science . The lack of availability of these complex carbohydrate...
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Emerg Top Life Sci (2018) 2 (3): 433–442.
Published: 18 October 2018
..., the characteristics of CHO glycosylation are summarized. Moreover, recent and current metabolic engineering strategies for tailoring glycoprotein fucosylation and sialylation in CHO cells, intensely investigated in the past decades, are described. One approach for reducing α1,6-fucosylation is through inhibiting...
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Emerg Top Life Sci (2018) 2 (3): 337–348.
Published: 11 September 2018
...Mattheos A.G. Koffas; Robert J. Linhardt; Asher Williams; Robert J. Linhardt; Mattheos A.G. Koffas With rising concerns about sustainable practices, environmental complications, and declining resources, metabolic engineers are transforming microorganisms into cellular factories for producing...
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Emerg Top Life Sci (2018) 2 (3): 377–388.
Published: 11 September 2018
... and differences between CTOs and CSOs, summarize the current preparation approaches of COs, and discuss the future research potentials and challenges in the production of well-defined COs in B. subtilis by metabolic engineering. Acid hydrolysis and oxidative degradation methods are the most widely applied...
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Emerg Top Life Sci (2018) 2 (3): 389–403.
Published: 06 August 2018
...-of-the-art systems and synthetic biology tools, a range of small to complex glycosylated natural products have been produced from microbes using a simple and sustainable fermentation approach. In this context, this review covers recent notable metabolic engineering approaches used for the biosynthesis...