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Keywords: synthetic cells
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Emerg Top Life Sci (2019) 3 (5): 615–622.
Published: 18 October 2019
...Hagan Bayley; Idil Cazimoglu; Charlotte E.G. Hoskin While significant advances have been achieved with non-living synthetic cells built from the bottom-up, less progress has been made with the fabrication of synthetic tissues built from such cells. Synthetic tissues comprise patterned three...
Emerg Top Life Sci (2019) 3 (5): 517–527.
Published: 04 September 2019
...Oliver R. Maguire; Wilhelm T.S. Huck The goal of creating a synthetic cell necessitates the development of reaction networks which will underlie all of its behaviours. Recent developments in in vitro systems, based upon both DNA and enzymes, have created networks capable of a range of behaviours...
Emerg Top Life Sci (2019) 3 (5): 597–607.
Published: 04 September 2019
... of Biology and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . artificial cell biotechnology synthetic biology synthetic cells Communication can be mediated through direct physical contact between artificial cells as opposed to the release of chemical signals...
Emerg Top Life Sci (2019) 3 (5): 567–571.
Published: 04 September 2019
...Alexander F. Mason; Jan C.M. van Hest Cells, the discrete living systems that comprise all life on Earth, are a boundless source of inspiration and motivation for many researchers in the natural sciences. In the field of bottom-up synthetic cells, researchers seek to create multifaceted, self...
Emerg Top Life Sci (2019) 3 (5): 587–595.
Published: 28 August 2019
...Friedrich C. Simmel One approach towards the creation of bottom-up synthetic biological systems of higher complexity relies on the subcompartmentalization of synthetic cell structures using artificially generated organelles — roughly mimicking the architecture of eukaryotic cells. Organelles create...
Emerg Top Life Sci (2019) 3 (5): 559–566.
Published: 20 August 2019
...Siddharth Deshpande; Cees Dekker In this article, we argue that on-chip microfluidic systems provide an attractive technology when it comes to designing synthetic cells. We emphasize the importance of the surrounding environment for both living systems in nature and for developing artificial self...
Emerg Top Life Sci (2019) 3 (5): 543–549.
Published: 23 July 2019
... that are essential for membrane related processes. As a first step towards synthetic cells, an in vitro phospholipid biosynthesis pathway has been constructed that utilizes fatty acids as precursors to produce a wide variety of phospholipid species, thereby driving membrane growth. This now needs to be developed...