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Issues

ISSN 0071-1365
EISSN 1744-1358
In this Issue

Structure-Based Drug Design: Insights from Academia and Industry

Review Articles

Essays in Biochemistry (8 November 2017) 61 (5): 431–437.
Essays in Biochemistry (8 November 2017) 61 (5): 439–452.
Essays in Biochemistry (8 November 2017) 61 (5): 453–464.
Essays in Biochemistry (8 November 2017) 61 (5): 465–473.
Essays in Biochemistry (8 November 2017) 61 (5): 475–484.
Essays in Biochemistry (8 November 2017) 61 (5): 485–493.
Essays in Biochemistry (8 November 2017) 61 (5): 495–503.
Essays in Biochemistry (8 November 2017) 61 (5): 505–516.
Essays in Biochemistry (8 November 2017) 61 (5): 517–527.
Essays in Biochemistry (8 November 2017) 61 (5): 529–542.
Essays in Biochemistry (8 November 2017) 61 (5): 543–560.
  • Cover Image

    Cover Image

    issue cover
    The small molecule inhibitor of the Wnt pathway CCT251545 (gold) bound to CDK8-cyclin C (PDB 5BNJ), with the 2Fo-Fc electron density superimposed as a blue chicken-wire mesh contoured at 1σ (blue), based the research of Dale et al. [Nat. Chem. Biol. (2015) 11, 973–980]. The inhibitor can be used as a chemical tool to explore the role of the Mediator complex in human disease. Image kindly provided by Paul Workman and Rob van Montfort.
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